{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Shi T"],"funding":["Collaborative custom development of RNA probes"],"pagination":["2268"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12467871"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["13(9)"],"pubmed_abstract":["<b>Background/Objectives:</b> Gastric cancer (GC), a prevalent global malignancy and a leading cause of cancer-related mortality, has a poorly understood prognosis related to <i>TRIP13</i> expression. <i>TRIP13</i> has a recognized part in driving tumor progression across different cancer types, yet its precise role in GC remains beyond our full comprehension. Our study aimed to explore <i>TRIP13's</i> prognostic value and function in GC patients. <b>Methods</b>: We extensively explored <i>TRIP13's</i> influence on GC prognosis, functionality, and immune response by examining various cancer-related databases like UALCAN, GEPIA, GEO, and TIMER. Immunohistochemistry (IHC) staining was also conducted to assess the link between <i>TRIM13</i> and GC patient survival. <b>Results</b>: <i>TRIP13</"],"journal":["Biomedicines"],"pubmed_title":["Decoding TRIP13's Role in Gastric Cancer: Implications for Prognosis and Immune Response."],"pmcid":["PMC12467871"],"funding_grant_id":["P112213323"],"pubmed_authors":["Zhao A","Chen F","Shi T","Xia S","Shen Y","Dong R"],"additional_accession":[]},"is_claimable":false,"name":"Decoding TRIP13's Role in Gastric Cancer: Implications for Prognosis and Immune Response.","description":"<b>Background/Objectives:</b> Gastric cancer (GC), a prevalent global malignancy and a leading cause of cancer-related mortality, has a poorly understood prognosis related to <i>TRIP13</i> expression. <i>TRIP13</i> has a recognized part in driving tumor progression across different cancer types, yet its precise role in GC remains beyond our full comprehension. Our study aimed to explore <i>TRIP13's</i> prognostic value and function in GC patients. <b>Methods</b>: We extensively explored <i>TRIP13's</i> influence on GC prognosis, functionality, and immune response by examining various cancer-related databases like UALCAN, GEPIA, GEO, and TIMER. Immunohistochemistry (IHC) staining was also conducted to assess the link between <i>TRIM13</i> and GC patient survival. <b>Results</b>: <i>TRIP13</","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-06-30T03:24:11.858Z","creation":"2026-06-30T03:16:37.791Z"},"accession":"S-EPMC12467871","cross_references":{"pubmed":["41007830"],"doi":["10.3390/biomedicines13092268"]}}