{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Premusz V"],"funding":["Ministry of Culture and Innovation","Ministry of Culture and Innovation, the National Research, Development, and Innovation Fund"],"pagination":["6552"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12470367"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(18)"],"pubmed_abstract":["<b>Background/Objectives:</b> Infertility imposes substantial psychosocial burdens on affected individuals, often resulting in a decline in quality of life comparable to that experienced in chronic diseases. Exploring lifestyle and health awareness-related factors is essential to develop complex, multidisciplinary approaches. This study investigated the associations between the components of 24-h movement behaviour (physical activity, sedentary lifestyle, sleep), health literacy, fertility awareness, and general and infertility-specific quality of life. Additionally, the study assessed whether these factors could predict quality of life outcomes in women living with infertility. <b>Methods:</b> A cross-sectional study was conducted using questionnaire-based data collection in four fertility centres in Hungary. The convenience sample included 361 women aged 18-45 years with a documented infertility diagnosis. Validated questionnaires were used to assess health literacy (BRIEF), fertility awareness (FAS), physical activity (GPAQ-H), sleep quality (AIS), and quality of life (WHOQOL-BREF and FertiQoL). Data analysis included Kolmogorov-Smirnov tests, Spearman correlations, and generalised linear modelling (GLM), with statistical significance set at <i>p</i> < 0.05. <b>Results:</b> Based on the FAS, 77.8% of participants (<i>n</i> = 274) self-reported being adequately informed; however, objective knowledge scores accounted for only 48.5% of the possible total, indicating limited knowledge. Fertility awareness positively correlated with recreational physical activity (ρ = 0.156; <i>p</i> = 0.003). Recreational physical activity showed low but significant positive associations with all quality-of-life dimensions (e.g., psychological well-being: r = 0.177; <i>p</i> ≤ 0.002), whereas sedentary time was negatively associated with psychological well-being (r = -0.109) and social relationships (r = -0.118). Sleep duration correlated positively while sleep quality problems correlated negatively with FertiQoL scores (r = -0.339; <i>p</i> ≤ 0.001). Better sleep quality, lower sedentary time, and higher health literacy were positive predictors of infertility-specific quality of life, whereas higher fertility awareness showed a paradoxical adverse effect. <b>Conclusions:</b> These findings highlight the role of 24-h movement behaviour and health awareness in improving quality of life among women with infertility. The study supports the need for tailored, multi-component lifestyle interventions to promote physical, mental, and psycho-social well-being."],"journal":["Journal of clinical medicine"],"pubmed_title":["24-Hour Movement Behaviour and Health Awareness as Possible Predictors of Infertility-Related Quality of Life."],"pmcid":["PMC12470367"],"funding_grant_id":["EKÖP-24-4-II-PTE-345","RRF-2.3.1-21-2022-00012","NKFI FK-147404"],"pubmed_authors":["Acs P","Makai A","Kovacs K","Skriba E","Tandor Z","Szmatona G","Kovacs R","Veres-Balajti I","Premusz V","Varnagy A"],"additional_accession":[]},"is_claimable":false,"name":"24-Hour Movement Behaviour and Health Awareness as Possible Predictors of Infertility-Related Quality of Life.","description":"<b>Background/Objectives:</b> Infertility imposes substantial psychosocial burdens on affected individuals, often resulting in a decline in quality of life comparable to that experienced in chronic diseases. Exploring lifestyle and health awareness-related factors is essential to develop complex, multidisciplinary approaches. This study investigated the associations between the components of 24-h movement behaviour (physical activity, sedentary lifestyle, sleep), health literacy, fertility awareness, and general and infertility-specific quality of life. Additionally, the study assessed whether these factors could predict quality of life outcomes in women living with infertility. <b>Methods:</b> A cross-sectional study was conducted using questionnaire-based data collection in four fertility centres in Hungary. The convenience sample included 361 women aged 18-45 years with a documented infertility diagnosis. Validated questionnaires were used to assess health literacy (BRIEF), fertility awareness (FAS), physical activity (GPAQ-H), sleep quality (AIS), and quality of life (WHOQOL-BREF and FertiQoL). Data analysis included Kolmogorov-Smirnov tests, Spearman correlations, and generalised linear modelling (GLM), with statistical significance set at <i>p</i> < 0.05. <b>Results:</b> Based on the FAS, 77.8% of participants (<i>n</i> = 274) self-reported being adequately informed; however, objective knowledge scores accounted for only 48.5% of the possible total, indicating limited knowledge. Fertility awareness positively correlated with recreational physical activity (ρ = 0.156; <i>p</i> = 0.003). Recreational physical activity showed low but significant positive associations with all quality-of-life dimensions (e.g., psychological well-being: r = 0.177; <i>p</i> ≤ 0.002), whereas sedentary time was negatively associated with psychological well-being (r = -0.109) and social relationships (r = -0.118). Sleep duration correlated positively while sleep quality problems correlated negatively with FertiQoL scores (r = -0.339; <i>p</i> ≤ 0.001). Better sleep quality, lower sedentary time, and higher health literacy were positive predictors of infertility-specific quality of life, whereas higher fertility awareness showed a paradoxical adverse effect. <b>Conclusions:</b> These findings highlight the role of 24-h movement behaviour and health awareness in improving quality of life among women with infertility. The study supports the need for tailored, multi-component lifestyle interventions to promote physical, mental, and psycho-social well-being.","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-05-01T03:21:09.38Z","creation":"2026-05-01T03:11:24.177Z"},"accession":"S-EPMC12470367","cross_references":{"pubmed":["41010755"],"doi":["10.3390/jcm14186552"]}}