{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Lang B"],"funding":["Natural Science Foundation of Inner Mongolia Autonomous Region Project","Domestic Collaboration Projects of the Shanghai Municipal Commission of Science and Technology","Science and Technology Cooperation Program of Shanghai Jiao Tong in Inner Mongolia Autonomous Region - Action Plan of Shanghai Jiao Tong University for Revitalizing Inner Mongolia through Science and Technology","Shanghai Agricultural Science and Technology Innovation Project of Shanghai Municipal Agricultural and Rural Committee","National Key Research and Development Program of China"],"pagination":["629"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12470592"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["11(9)"],"pubmed_abstract":["The pathogenic plant fungus <i>Bipolaris maydis</i> is responsible for southern corn leaf blight (SCLB), a widespread agricultural disease that significantly reduces maize yield in various agroecological zones. The present research focuses on characterizing the role of <i>Trichoderma harzianum</i> cellobiohydrolase (CBH) Thph2 in induced maize resistance to SCLB by triggering the production of reactive oxygen species (ROS) in leaves. First of all, we demonstrated the potential activities of Thph2 in triggering ROS burst and PDC in a model plant, <i>Nicotiana benthamiana</i>. Cell death, ROS burst, and programmed cell death (PCD) were observed in <i>N. benthamiana</i> leaves following transient expression of Thph2, indicating its defensive role against <i>Sclerotinia sclerotiorum</i> infect"],"journal":["Journal of fungi (Basel, Switzerland)"],"pubmed_title":["&lt;i&gt;Trichoderma harzianum&lt;/i&gt; Cellobiohydrolase Thph2 Induces Reactive Oxygen Species-Mediated Resistance Against Southern Corn Leaf Blight in Maize."],"pmcid":["PMC12470592"],"funding_grant_id":["2024-02-08-00-12-F00004","2023MS03045","2023YFD1401503","KJXM2023-12-01","24010701500"],"pubmed_authors":["Liu H","Chen J","Zhang X","Lang B","Si G","Zhang C","Wang J"],"additional_accession":[]},"is_claimable":false,"name":"&lt;i&gt;Trichoderma harzianum&lt;/i&gt; Cellobiohydrolase Thph2 Induces Reactive Oxygen Species-Mediated Resistance Against Southern Corn Leaf Blight in Maize.","description":"The pathogenic plant fungus <i>Bipolaris maydis</i> is responsible for southern corn leaf blight (SCLB), a widespread agricultural disease that significantly reduces maize yield in various agroecological zones. The present research focuses on characterizing the role of <i>Trichoderma harzianum</i> cellobiohydrolase (CBH) Thph2 in induced maize resistance to SCLB by triggering the production of reactive oxygen species (ROS) in leaves. First of all, we demonstrated the potential activities of Thph2 in triggering ROS burst and PDC in a model plant, <i>Nicotiana benthamiana</i>. Cell death, ROS burst, and programmed cell death (PCD) were observed in <i>N. benthamiana</i> leaves following transient expression of Thph2, indicating its defensive role against <i>Sclerotinia sclerotiorum</i> infect","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Aug","modification":"2026-05-01T03:22:20.232Z","creation":"2026-05-01T03:11:08.66Z"},"accession":"S-EPMC12470592","cross_references":{"pubmed":["41003175"],"doi":["10.3390/jof11090629"]}}