{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Tran QA"],"funding":["the Ministry of Education and Training, Vietnam"],"pagination":["723"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12473341"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["13(9)"],"pubmed_abstract":["This study investigates the effects of Bisphenol A (BPA)-a ubiquitous endocrine disruptor-on the swimming behavior of the rotifer <i>Brachionus plicatilis</i>. Across a 0-40 ppm gradient, a biphasic response was observed, with swimming speed peaking at 20 ppm (100.42 ± 12.17 µm/s) and then significantly declining by 43% to 57.58 ± 30.59 µm/s at 40 ppm (Tukey, <i>p</i> < 0.05). Speed-frequency plots revealed co-existing hyper- and hypoactive sub-populations at 10-30 ppm, whereas severe inhibition dominated at 40 ppm. Additionally, temporal analysis confirmed that BPA effects were both concentration- and time-dependent, with the mean speed at 10 ppm declining only slightly over time (slope ≈ -0.8), whereas at 40 ppm, the decrease was an order of magnitude steeper (slope ≈ -16.9). Additionall"],"journal":["Toxics"],"pubmed_title":["Behavioral Disruption in &lt;i&gt;Brachionus plicatilis&lt;/i&gt; Exposed to Bisphenol A: A Locomotion-Based Assessment."],"pmcid":["PMC12473341"],"funding_grant_id":["B2023.DNA.20"],"pubmed_authors":["Phan NT","Trinh-Dang M","Tran QA","Mai HT","Phan TLT","Tran-Nguyen QA"],"additional_accession":[]},"is_claimable":false,"name":"Behavioral Disruption in &lt;i&gt;Brachionus plicatilis&lt;/i&gt; Exposed to Bisphenol A: A Locomotion-Based Assessment.","description":"This study investigates the effects of Bisphenol A (BPA)-a ubiquitous endocrine disruptor-on the swimming behavior of the rotifer <i>Brachionus plicatilis</i>. Across a 0-40 ppm gradient, a biphasic response was observed, with swimming speed peaking at 20 ppm (100.42 ± 12.17 µm/s) and then significantly declining by 43% to 57.58 ± 30.59 µm/s at 40 ppm (Tukey, <i>p</i> < 0.05). Speed-frequency plots revealed co-existing hyper- and hypoactive sub-populations at 10-30 ppm, whereas severe inhibition dominated at 40 ppm. Additionally, temporal analysis confirmed that BPA effects were both concentration- and time-dependent, with the mean speed at 10 ppm declining only slightly over time (slope ≈ -0.8), whereas at 40 ppm, the decrease was an order of magnitude steeper (slope ≈ -16.9). Additionall","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Aug","modification":"2026-05-02T03:11:26.509Z","creation":"2026-05-02T03:08:04.423Z"},"accession":"S-EPMC12473341","cross_references":{"pubmed":["41012344"],"doi":["10.3390/toxics13090723"]}}