biostudies-literatureFerreira MADSFiocruz; Fapeam; CAPES249https://www.ebi.ac.uk/biostudies/studies/S-EPMC12474516biostudies-literatureUnknown10(9)Malaria continues to affect millions of people around the world. Current control strategies have not been sufficient, and additional tools are required for malaria elimination. A promising approach is the use of bacteria from the mosquito microbiota, such as the Su_YN1 <i>Serratia ureilytica</i> bacterium, which is shown to strongly impair the development of <i>P. falciparum</i> and <i>P. berghei</i> in <i>Anopheles</i> mosquitoes. To evaluate the potential of using <i>S. ureilytica</i> Su_YN1 to block the <i>Plasmodium</i> parasite in South American vectors, we investigated its effects on mosquito fitness and survival. We found that this bacterium does not affect the longevity, blood feeding, fecundity and fertility of <i>Anopheles aquasalis</i>, an important South American vector. OveralTropical medicine and infectious diseaseCompatibility of &lt;i&gt;Serratia ureylitica&lt;/i&gt; Su_YN1, Malaria Transmission-Blocking Bacterium, with the &lt;i&gt;Anopheles aquasalis&lt;/i&gt; Vector.PMC12474516Fiocruz (Programa Inova - Call Nº04/2022), Fapeam (Programa Fixação de Jovens Doutores, call FAP/CNPq nº 003/2022, ILMD/Fiocruz (PROEP), CAPES 001.Rocha EMde Andrade PPRios-Velasquez CMMoreira LARoque RAMartins ESDRSilva LAFerreira MADSWang SCarmo EJDLalwani PJKatak RMJacobs-Lorena MCampos KMMfalseCompatibility of &lt;i&gt;Serratia ureylitica&lt;/i&gt; Su_YN1, Malaria Transmission-Blocking Bacterium, with the &lt;i&gt;Anopheles aquasalis&lt;/i&gt; Vector.Malaria continues to affect millions of people around the world. Current control strategies have not been sufficient, and additional tools are required for malaria elimination. A promising approach is the use of bacteria from the mosquito microbiota, such as the Su_YN1 <i>Serratia ureilytica</i> bacterium, which is shown to strongly impair the development of <i>P. falciparum</i> and <i>P. berghei</i> in <i>Anopheles</i> mosquitoes. To evaluate the potential of using <i>S. ureilytica</i> Su_YN1 to block the <i>Plasmodium</i> parasite in South American vectors, we investigated its effects on mosquito fitness and survival. We found that this bacterium does not affect the longevity, blood feeding, fecundity and fertility of <i>Anopheles aquasalis</i>, an important South American vector. Overal2025-01-01T00:00:00Z2025 Aug2026-05-03T03:14:35.115Z2026-05-03T03:10:58.392ZS-EPMC124745164100355910.3390/tropicalmed10090249