{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["135(10)"],"submitter":["Bowen AJ"],"pubmed_abstract":["<h4>Objective</h4>There is currently not a marker of disease severity in idiopathic subglottic stenosis (iSGS). Our objective was to characterize iSGS patients' disease severity using endoscopic surgery rates.<h4>Methods</h4>This was a two-center retrospective analysis of iSGS patients with a minimum of 4 years of follow up following an initial endoscopic procedure (laser wedge excision (LWE) or endoscopic dilation (ED)). Disease severity was classified into Groups A-C, based on whether patients had fewer (Group A), the same number (Group B), or more surgeries (Group C) in years 3-5 compared to years 1 and 2. Disease severity proportions were compared across institutions using chi-square analysis. Nonparametric testing compared clinical characteristics such as age, BMI, and GERD across sev"],"journal":["The Laryngoscope"],"pagination":["3766-3773"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12475557"],"repository":["biostudies-literature"],"pubmed_title":["Characterizing Disease Severity Through Surgical Recurrence Rates in Idiopathic Subglottic Stenosis."],"pmcid":["PMC12475557"],"pubmed_authors":["Ali H","Bayan S","Ekbom D","Koster M","Bowen AJ","Ring S","Davis R","Khalil Y","Francis DO","Awadallah A","McCalla M","Roitman A","Leverson G","Xie K","Dailey SH","Edell E"],"additional_accession":[]},"is_claimable":false,"name":"Characterizing Disease Severity Through Surgical Recurrence Rates in Idiopathic Subglottic Stenosis.","description":"<h4>Objective</h4>There is currently not a marker of disease severity in idiopathic subglottic stenosis (iSGS). Our objective was to characterize iSGS patients' disease severity using endoscopic surgery rates.<h4>Methods</h4>This was a two-center retrospective analysis of iSGS patients with a minimum of 4 years of follow up following an initial endoscopic procedure (laser wedge excision (LWE) or endoscopic dilation (ED)). Disease severity was classified into Groups A-C, based on whether patients had fewer (Group A), the same number (Group B), or more surgeries (Group C) in years 3-5 compared to years 1 and 2. Disease severity proportions were compared across institutions using chi-square analysis. Nonparametric testing compared clinical characteristics such as age, BMI, and GERD across sev","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Oct","modification":"2026-06-03T23:09:20.541Z","creation":"2026-05-02T03:11:59.651Z"},"accession":"S-EPMC12475557","cross_references":{"pubmed":["40396584"],"doi":["10.1002/lary.32280"]}}