biostudies-literatureBucayu RFTNational Institute of Allergy and Infectious DiseasesPEdiatric Antifungal Comparative EffectivenessCenters for Disease Control and PreventionCanada Research Chair in Pediatric Oncology Supportive CareNIDDK NIH HHSNIAID NIH HHSCystic Fibrosis FoundationAHRQNational Institutes of Health, Food Drug and AministrationNational Institute of Diabetes, Digestive, and Kidney DiseasesNational Institutes of Health633-638https://www.ebi.ac.uk/biostudies/studies/S-EPMC12476979biostudies-literatureUnknown13(12)Of 319 children with invasive candidiasis, 67 (21%) transitioned from intravenous to enteral antifungal therapy. Eight (12%) transitioned back to intravenous antifungal therapy, one due to perceived treatment failure defined by clinical progression or worsening. Global treatment response at study completion was successful in 66 participants who transitioned to enteral therapy.Journal of the Pediatric Infectious Diseases SocietyTransition to Enteral Triazole Antifungal Therapy for Pediatric Invasive Candidiasis: Secondary Analysis of a Multicenter Cohort Study Conducted by the Pediatric Fungal Network.PMC124769791K12DK111028K12 DK111028R01 AI1033155R01AI103315Wattier RLAftandilian CMaron GArrieta ACLutsar IBelani KDanziger-Isakov LChakrabarti AJohnson SKVora SBRajan SFisher BTTribble ACDulek DPalazzi DLSteinbach WJSalvatore CMKnackstedt EDSung LRoilides EHalasa NNolt DArdura MIGonzalez BERomero JSoler-Palacin PPong ABucayu RFTAbzug MJBoge CLKCarlesse FMuller WJLopez-Medina EGreen MYildirim IBerman DMAviles-Robles MYin DECastagnola ESharma TSHuppler ARfalseTransition to Enteral Triazole Antifungal Therapy for Pediatric Invasive Candidiasis: Secondary Analysis of a Multicenter Cohort Study Conducted by the Pediatric Fungal Network.Of 319 children with invasive candidiasis, 67 (21%) transitioned from intravenous to enteral antifungal therapy. Eight (12%) transitioned back to intravenous antifungal therapy, one due to perceived treatment failure defined by clinical progression or worsening. Global treatment response at study completion was successful in 66 participants who transitioned to enteral therapy.2024-01-01T00:00:00Z2024 Dec2026-06-03T23:22:36.379Z2026-05-03T03:11:12.907ZS-EPMC124769793951340010.1093/jpids/piae116