{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Holtman S"],"funding":["NICHD NIH HHS","NCATS NIH HHS","National Institute for Health","NIDDK NIH HHS"],"pagination":["zsae273"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12477115"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["48(2)"],"pubmed_abstract":["<h4>Study objectives</h4>Evaluate objectively measured circadian rhythms following 1-week of at-home sleep extension in habitually short-sleeping adolescents.<h4>Methods</h4>Twenty-six participants (16.1 ± 1.2 years, 69% female, and 65% White non-Hispanic) with insufficient sleep (≤7 h on school nights) were randomized to 1 week of typical sleep (TS; usual school schedule) and sleep extension (EXT; ≥1-h additional time in bed) in counterbalanced order with a 1-month washout between conditions. Home monitoring of actigraphy-estimated sleep and light exposure was assessed during both weeks. Hourly in-laboratory evening/morning dim-light salivary melatonin samples were obtained and onset (DLMOn) and offset (DLMOff) were calculated following each condition.<h4>Results</h4>Sleep duration increa"],"journal":["Sleep"],"pubmed_title":["Changes in circadian timing following a 1-week in-home sleep extension manipulation in habitually short-sleeping adolescents."],"pmcid":["PMC12477115"],"funding_grant_id":["NIH NCATS Colorado CTSA UL1 TR002535","K23 DK117021","NIDDK K23DK117021","NIH BIRCWH K12HD057022","R03 DK131225","UL1 TR002535","K12 HD057022"],"pubmed_authors":["Bowen AE","Nadeau KJ","Wright KP","Cooper E","Holtman S","Hawkins S","Cree MG","Simon SL","Brinton JT"],"additional_accession":[]},"is_claimable":false,"name":"Changes in circadian timing following a 1-week in-home sleep extension manipulation in habitually short-sleeping adolescents.","description":"<h4>Study objectives</h4>Evaluate objectively measured circadian rhythms following 1-week of at-home sleep extension in habitually short-sleeping adolescents.<h4>Methods</h4>Twenty-six participants (16.1 ± 1.2 years, 69% female, and 65% White non-Hispanic) with insufficient sleep (≤7 h on school nights) were randomized to 1 week of typical sleep (TS; usual school schedule) and sleep extension (EXT; ≥1-h additional time in bed) in counterbalanced order with a 1-month washout between conditions. Home monitoring of actigraphy-estimated sleep and light exposure was assessed during both weeks. Hourly in-laboratory evening/morning dim-light salivary melatonin samples were obtained and onset (DLMOn) and offset (DLMOff) were calculated following each condition.<h4>Results</h4>Sleep duration increa","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Feb","modification":"2026-06-04T00:12:14.035Z","creation":"2026-05-03T03:11:56.224Z"},"accession":"S-EPMC12477115","cross_references":{"pubmed":["39582182"],"doi":["10.1093/sleep/zsae273"]}}