biostudies-literatureHoerger MAmerican Cancer SocietyNational Cancer InstituteNCI NIH HHSNational Institute of General Medical SciencesNIGMS NIH HHS978-984https://www.ebi.ac.uk/biostudies/studies/S-EPMC12477991biostudies-literatureUnknown31(6)<h4>Background</h4>Informed treatment decision-making necessitates accurate prognostication, including predictions about quality of life.<h4>Aims</h4>We examined whether oncologists, patients with advanced cancer, and caregivers accurately predict patients' future quality of life and whether these predictions are prospectively associated with end-of-life care and bereavement.<h4>Materials & methods</h4>We conducted secondary analyses of clinical trial data. Patients with advanced cancer (n = 156), caregivers (n = 156), and oncologists (n = 38) predicted patient quality of life 3 months into the future. Patients subsequently rated their quality of life 3 months later. Medical record data documented chemotherapy and emergency department (ED)/inpatient visits in the 30 days before death (n = Psycho-oncologyPatient, caregiver, and oncologist predictions of quality of life in advanced cancer: Accuracy and associations with end-of-life care and caregiver bereavement.PMC12477991R01 CA140419R01 CA168387UG1 CA189961U54 GM104940Kravitz RLAlonzi SMalhotra KDuberstein PEpstein RMohile SGMossman BPrigerson HGHoerger MFenton JJGramling RfalsePatient, caregiver, and oncologist predictions of quality of life in advanced cancer: Accuracy and associations with end-of-life care and caregiver bereavement.<h4>Background</h4>Informed treatment decision-making necessitates accurate prognostication, including predictions about quality of life.<h4>Aims</h4>We examined whether oncologists, patients with advanced cancer, and caregivers accurately predict patients' future quality of life and whether these predictions are prospectively associated with end-of-life care and bereavement.<h4>Materials & methods</h4>We conducted secondary analyses of clinical trial data. Patients with advanced cancer (n = 156), caregivers (n = 156), and oncologists (n = 38) predicted patient quality of life 3 months into the future. Patients subsequently rated their quality of life 3 months later. Medical record data documented chemotherapy and emergency department (ED)/inpatient visits in the 30 days before death (n = 2022-01-01T00:00:00Z2022 Jun2026-06-04T00:09:36.097Z2026-05-03T03:12:22.851ZS-EPMC124779913508892610.1002/pon.5887