biostudies-literatureXiao Lthe Australian Government via 2020 Medical Research Future Fund2020 NHMRC/The Dementia Centre for Research Collaboration (DCRC) World-Class Research Project Grantse70747https://www.ebi.ac.uk/biostudies/studies/S-EPMC12479211biostudies-literatureUnknown21(10)<h4>Introduction</h4>We conducted a virtual iSupport Program intervention for carers of people living with dementia (PLWD).<h4>Methods</h4>We applied a pragmatic randomized controlled trial to evaluate a multicomponent program delivered virtually in four organizations (July 2022 to December 2024). The primary outcome was quality of life (QoL) of carers and PLWD at 12 months post-baseline, and the secondary outcomes were carers' self-efficacy, social support, reactions to behavior, PLWD's behavior frequency, hospital admissions, and emergency department presentations.<h4>Results</h4>One hundred forty-nine carers enrolled in the study. The intervention group reported increased mental-health-related QoL points of 12.0 (p < 0.001), self-efficacy points of 14.8 to 18.5 (p < 0.001), social support points of 0.25 (p < 0.028), reduced reactions to behavior points of -0.25 (p < 0.028), and a 60% lower hospital admission rate (p = 0.045) at 12 months compared with the usual care group.<h4>Discussion</h4>The virtual iSupport Program showed benefits for both carers and PLWD in a 12-month intervention.<h4>Trial registration</h4>Australia New Zealand Clinical Trials Registry: ACTRN12622000199718.<h4>Highlights</h4>A total of 149 dementia carers participated in the virtual iSupport program intervention trial. The program included skills training, peer support, and access to care services. The program improved mental health-related quality of life for carers. The program improved self-efficacy, social support, and reduced distress for carers. The program reduced 60% hospital admission rate for people with dementia.Alzheimer's & dementia : the journal of the Alzheimer's AssociationEffects of a virtual iSupport Program on carers and people with dementia.PMC12479211application ID: 2008321Meyer CTan KPChen LOttaway MRatcliffe JUllah SXiao LAndrade AQMcKechnie SWang YKitson ATran KWhitehead CYu YChapman MfalseEffects of a virtual iSupport Program on carers and people with dementia.<h4>Introduction</h4>We conducted a virtual iSupport Program intervention for carers of people living with dementia (PLWD).<h4>Methods</h4>We applied a pragmatic randomized controlled trial to evaluate a multicomponent program delivered virtually in four organizations (July 2022 to December 2024). The primary outcome was quality of life (QoL) of carers and PLWD at 12 months post-baseline, and the secondary outcomes were carers' self-efficacy, social support, reactions to behavior, PLWD's behavior frequency, hospital admissions, and emergency department presentations.<h4>Results</h4>One hundred forty-nine carers enrolled in the study. The intervention group reported increased mental-health-related QoL points of 12.0 (p < 0.001), self-efficacy points of 14.8 to 18.5 (p < 0.001), social support points of 0.25 (p < 0.028), reduced reactions to behavior points of -0.25 (p < 0.028), and a 60% lower hospital admission rate (p = 0.045) at 12 months compared with the usual care group.<h4>Discussion</h4>The virtual iSupport Program showed benefits for both carers and PLWD in a 12-month intervention.<h4>Trial registration</h4>Australia New Zealand Clinical Trials Registry: ACTRN12622000199718.<h4>Highlights</h4>A total of 149 dementia carers participated in the virtual iSupport program intervention trial. The program included skills training, peer support, and access to care services. The program improved mental health-related quality of life for carers. The program improved self-efficacy, social support, and reduced distress for carers. The program reduced 60% hospital admission rate for people with dementia.2025-01-01T00:00:00Z2025 Oct2026-06-03T23:14:39.099Z2026-05-02T03:11:42.047ZS-EPMC124792114102330910.1002/alz.70747