biostudies-literatureDu HZhejiang Provincial Traditional Chinese Medicine Science and Technology Program - Modernization InitiativeZhejiang Provincial "Pioneer" and "Leading Goose" R&D ProgramMajor Project of the Science and Technology Department of the National Administration of Traditional Chinese Medicine and Administration of Traditional Chinese Medicine of Zhejiang Province Collaborative Technology ProgramResearch Project of Zhejiang Chinese Medical UniversityZhejiang Provincial Traditional Chinese Medicine Science and Technology Program Project33558https://www.ebi.ac.uk/biostudies/studies/S-EPMC12480702biostudies-literatureUnknown15(1)Patients with idiopathic scoliosis require regular radiation-less follow-up such as ultrasound. Automated labeling reduces traditional ultrasound manual labeling errors. We enrolled 80 patients with idiopathic scoliosis between February 2024 and June 2024. We evaluated both intra- and inter-operator reliability of the ultrasound curve angle (UCA) and ultrasound lamina angle (USLA) and compared three-dimensional ultrasound assessments with conventional X-ray imaging to evaluate the validity and reliability of ultrasound measurements (UCA and USLA) against established radiographic benchmarks, including Cobb angle, thoracic kyphosis, and lumbar lordosis. Reliability assessments were conducted using the intraclass correlation coefficient (ICC). The validity of the UCA and USLA measurements was rigorously analyzed by comparing them against established radiographic benchmarks using Pearson correlation coefficients and Bland-Altman plots. ICC analyses confirmed robust ultrasound measurement reliability. Validity evaluations revealed a pronounced linear correlation between the UCA and coronal Cobb angle. Bland-Altman plots showed a strong correlation between ultrasound and radiologic measurements in the coronal plane. Automated ultrasound represents a promising diagnostic tool for monitoring conservative treatments in the future.Scientific reportsValidity and reliability of 3D automatic ultrasound imaging for measuring coronal and sagittal angles in idiopathic scoliosis.PMC124807022022JKJNTZ222022ZX01520230174272024C031822024ZL450Lv LLiang JDong JDu HHan XLi QLiu CChen XChen SWu YWang KZhao XfalseValidity and reliability of 3D automatic ultrasound imaging for measuring coronal and sagittal angles in idiopathic scoliosis.Patients with idiopathic scoliosis require regular radiation-less follow-up such as ultrasound. Automated labeling reduces traditional ultrasound manual labeling errors. We enrolled 80 patients with idiopathic scoliosis between February 2024 and June 2024. We evaluated both intra- and inter-operator reliability of the ultrasound curve angle (UCA) and ultrasound lamina angle (USLA) and compared three-dimensional ultrasound assessments with conventional X-ray imaging to evaluate the validity and reliability of ultrasound measurements (UCA and USLA) against established radiographic benchmarks, including Cobb angle, thoracic kyphosis, and lumbar lordosis. Reliability assessments were conducted using the intraclass correlation coefficient (ICC). The validity of the UCA and USLA measurements was rigorously analyzed by comparing them against established radiographic benchmarks using Pearson correlation coefficients and Bland-Altman plots. ICC analyses confirmed robust ultrasound measurement reliability. Validity evaluations revealed a pronounced linear correlation between the UCA and coronal Cobb angle. Bland-Altman plots showed a strong correlation between ultrasound and radiologic measurements in the coronal plane. Automated ultrasound represents a promising diagnostic tool for monitoring conservative treatments in the future.2025-01-01T00:00:00Z2025 Sep2026-06-03T23:29:18.531Z2026-05-03T03:11:15.378ZS-EPMC124807024102300510.1038/s41598-025-18538-1