{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Li Q"],"funding":["National Natural Science Foundation of China (National Science Foundation of China)"],"pagination":["1579"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12480761"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["12(1)"],"pubmed_abstract":["This data descriptor presents a multi-omics resource for Crassostrea gigas and Crassostrea angulata, comprising genomic variants and transcriptomic profiles relevant to fatty acid metabolism traits. A 458-individual F<sub>2</sub> hybrid population genotyped with a 100 K SNP array identified 344 SNPs and 742 candidate genes linked to C18:3ω3, EPA, and DHA variation. KEGG analysis highlighted 24 key genes, with 23 validated via GS-assisted GWAS, dominant genotype screening, and wild population resequencing. Differential expression analysis revealed 458 DEGs (266 between high/low EPA + DHA groups; 192 between species), overlapping with 152 genes from GWAS and selective sweeps. This integrated dataset provides foundational genetic references for studying ω-3 fatty acid dynamics, enabling futur"],"journal":["Scientific data"],"pubmed_title":["Genetic Resources for Research on the Regulatory Mechanism of ω-3 Fatty Acids in Oysters."],"pmcid":["PMC12480761"],"funding_grant_id":["2022YFD2400304"],"pubmed_authors":["Zhang G","Cong R","Wang C","Qi H","Li Q","Wang W","Li L"],"additional_accession":[]},"is_claimable":false,"name":"Genetic Resources for Research on the Regulatory Mechanism of ω-3 Fatty Acids in Oysters.","description":"This data descriptor presents a multi-omics resource for Crassostrea gigas and Crassostrea angulata, comprising genomic variants and transcriptomic profiles relevant to fatty acid metabolism traits. A 458-individual F<sub>2</sub> hybrid population genotyped with a 100 K SNP array identified 344 SNPs and 742 candidate genes linked to C18:3ω3, EPA, and DHA variation. KEGG analysis highlighted 24 key genes, with 23 validated via GS-assisted GWAS, dominant genotype screening, and wild population resequencing. Differential expression analysis revealed 458 DEGs (266 between high/low EPA + DHA groups; 192 between species), overlapping with 152 genes from GWAS and selective sweeps. This integrated dataset provides foundational genetic references for studying ω-3 fatty acid dynamics, enabling futur","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-06-04T00:07:06.346Z","creation":"2026-05-03T03:12:26.605Z"},"accession":"S-EPMC12480761","cross_references":{"pubmed":["41022887"],"doi":["10.1038/s41597-025-05822-y"]}}