biostudies-literatureUnknown15(10)Persson KNasjonalforeningen for FolkehelsenThe Southern and Eastern Norway Regional Health AuthorityAlzheimer NederlandHorizon 2022KLINBEFORSKMemorabel Dementia Fellowship 2021<h4>Introduction</h4>Efficient and cost-effective diagnostic tools for supporting dementia assessment are increasingly important. We aimed to evaluate whether providing neuroradiologists with volumetric data from an automatic MRI software, NeuroQuant, enhanced the diagnostic accuracy of their visual MRI assessment.<h4>Methods</h4>Two neuroradiologists assessed brain MRIs from 366 patients (mean age 67.5 years, SD 9.2, and 52% females) with subjective cognitive decline (SCD, n 79), mild cognitive impairment (MCI, n 86), or dementia (n 201). The MCI and dementia patients were further diagnosed according to an etiology of Alzheimer's disease (AD, n 217) versus non-AD (n 70). In random order the neuroradiologists visually evaluated medial temporal lobe atrophy (MTA, scale 0-4) with and withoutBrain and behaviore70948https://www.ebi.ac.uk/biostudies/studies/S-EPMC12480925biostudies-literatureAutomatic MRI Volumetry Assisted Visual Assessment of the Medial Temporal Lobe in Clinical Dementia Work-Up.PMC12480925Knapskog ABPersson KBekkhus-Wetterberg PSelbæk GEdwin THSchellhorn TRhodius-Meester HFMEngedal KfalseAutomatic MRI Volumetry Assisted Visual Assessment of the Medial Temporal Lobe in Clinical Dementia Work-Up.<h4>Introduction</h4>Efficient and cost-effective diagnostic tools for supporting dementia assessment are increasingly important. We aimed to evaluate whether providing neuroradiologists with volumetric data from an automatic MRI software, NeuroQuant, enhanced the diagnostic accuracy of their visual MRI assessment.<h4>Methods</h4>Two neuroradiologists assessed brain MRIs from 366 patients (mean age 67.5 years, SD 9.2, and 52% females) with subjective cognitive decline (SCD, n 79), mild cognitive impairment (MCI, n 86), or dementia (n 201). The MCI and dementia patients were further diagnosed according to an etiology of Alzheimer's disease (AD, n 217) versus non-AD (n 70). In random order the neuroradiologists visually evaluated medial temporal lobe atrophy (MTA, scale 0-4) with and without2025-01-01T00:00:00Z2025 Oct2026-06-03T23:20:48.319Z2026-05-03T03:10:55.249ZS-EPMC124809254102471610.1002/brb3.70948