{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["25(10)"],"submitter":["Harrison SE"],"pubmed_abstract":["We prospectively examined whether psychological factors influence (a) respiratory tract infection (RTI) risk and (b) the mucosal immune response to exercise. In Study 1, n = 406 adults (67% male) recorded RTI symptoms for two weeks before and after a marathon. In Study 2, under controlled laboratory conditions, n = 45 adults (51% male) completed 60 min of running at 65% V̇O<sub>2peak</sub> (EX) and seated rest (CON) in randomised order. Anxiety, total mood disturbance (TMD) and perceived psychological stress were measured before exercise. Saliva collected pre- and post-exercise was analysed for secretory immunoglobulin A (SIgA). Fifty runners suffered an RTI post-marathon. Runners prospectively reporting high trait anxiety or TMD were more likely to suffer an RTI post-marathon (OR [95% CI]"],"journal":["European journal of sport science"],"pagination":["e70058"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12480926"],"repository":["biostudies-literature"],"pubmed_title":["Anxiety and Mood Disturbance Are Prospectively Associated With Respiratory Infection Risk and the Mucosal Immune Response to Exercise."],"pmcid":["PMC12480926"],"pubmed_authors":["Edwards JP","Roberts R","Walsh NP","Harrison SE"],"additional_accession":[]},"is_claimable":false,"name":"Anxiety and Mood Disturbance Are Prospectively Associated With Respiratory Infection Risk and the Mucosal Immune Response to Exercise.","description":"We prospectively examined whether psychological factors influence (a) respiratory tract infection (RTI) risk and (b) the mucosal immune response to exercise. In Study 1, n = 406 adults (67% male) recorded RTI symptoms for two weeks before and after a marathon. In Study 2, under controlled laboratory conditions, n = 45 adults (51% male) completed 60 min of running at 65% V̇O<sub>2peak</sub> (EX) and seated rest (CON) in randomised order. Anxiety, total mood disturbance (TMD) and perceived psychological stress were measured before exercise. Saliva collected pre- and post-exercise was analysed for secretory immunoglobulin A (SIgA). Fifty runners suffered an RTI post-marathon. Runners prospectively reporting high trait anxiety or TMD were more likely to suffer an RTI post-marathon (OR [95% CI]","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Oct","modification":"2026-06-04T00:02:23.895Z","creation":"2026-05-03T03:12:30.579Z"},"accession":"S-EPMC12480926","cross_references":{"pubmed":["41024702"],"doi":["10.1002/ejsc.70058"]}}