{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Tian Z"],"funding":["National Natural Science Foundation of China (National Science Foundation of China)"],"pagination":["1576"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12480977"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["12(1)"],"pubmed_abstract":["Phlomoides rotata (Duyiwei), a threatened Tibetan medicinal plant with anti-inflammatory and analgesic properties, has an understudied genome. We generated a chromosome-level assembly of its 4.12 Gb genome using Oxford Nanopore, PacBio HiFi, Illumina, and Hi-C sequencing, anchoring 22 pseudochromosomes (contig N50 = 173.16 Mb, scaffold N50 = 191.90 Mb). Annotation identified 70,881 protein-coding genes (99.3% complete via BUSCO). Comparative genomic analyses provide insights into the phylogenetic relationships of P. rotata. These data provide insights into high-altitude adaptation, bioactive compound biosynthesis, and evolutionary history, supporting conservation and drug development efforts."],"journal":["Scientific data"],"pubmed_title":["Chromosome-level Genome Assembly of the Tibetan Medicinal Plant Duyiwei (Phlomoides rotata)."],"pmcid":["PMC12480977"],"funding_grant_id":["31760127"],"pubmed_authors":["Tian Z","Zhang T","Chen J","La Q","Zeng Z","Wang J"],"additional_accession":[]},"is_claimable":false,"name":"Chromosome-level Genome Assembly of the Tibetan Medicinal Plant Duyiwei (Phlomoides rotata).","description":"Phlomoides rotata (Duyiwei), a threatened Tibetan medicinal plant with anti-inflammatory and analgesic properties, has an understudied genome. We generated a chromosome-level assembly of its 4.12 Gb genome using Oxford Nanopore, PacBio HiFi, Illumina, and Hi-C sequencing, anchoring 22 pseudochromosomes (contig N50 = 173.16 Mb, scaffold N50 = 191.90 Mb). Annotation identified 70,881 protein-coding genes (99.3% complete via BUSCO). Comparative genomic analyses provide insights into the phylogenetic relationships of P. rotata. These data provide insights into high-altitude adaptation, bioactive compound biosynthesis, and evolutionary history, supporting conservation and drug development efforts.","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-06-04T01:46:21.261Z","creation":"2026-05-04T03:13:44.45Z"},"accession":"S-EPMC12480977","cross_references":{"pubmed":["41022913"],"doi":["10.1038/s41597-025-05800-4"]}}