{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["15(9)"],"submitter":["Wei R"],"pubmed_abstract":["<h4>Introduction</h4>Coronary artery bypass grafting (CABG) is a standard treatment for coronary artery disease, particularly in patients with multivessel disease. Connecting the saphenous vein graft (SVG) to the right internal mammary artery (RIMA) instead of the aorta has been proposed as an alternative approach to minimise aortic manipulation and potentially improve graft patency. This study aims to determine whether the RIMA-SVG technique is non-inferior to the conventional Aorta (Ao)-SVG approach in terms of 1-year graft patency, while also comparing perioperative complications and short-term clinical outcomes.<h4>Methods and analysis</h4>This non-inferiority, single-centre, prospective, double-blind, randomised clinical trial will enrol 300 patients undergoing CABG. Participants will"],"journal":["BMJ open"],"pagination":["e104578"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12481333"],"repository":["biostudies-literature"],"pubmed_title":["RIMA-SVG versus Ao-SVG in coronary artery bypass grafting: protocol for a prospective, randomised, double-blind, non-inferiority and single-centre trial."],"pmcid":["PMC12481333"],"pubmed_authors":["He T","Liu K","Wei R","Zhu Z","Yu S","Piao H","Wang T","Huang M","Wang W","Jiang N","Zhang R","Zhu C"],"additional_accession":[]},"is_claimable":false,"name":"RIMA-SVG versus Ao-SVG in coronary artery bypass grafting: protocol for a prospective, randomised, double-blind, non-inferiority and single-centre trial.","description":"<h4>Introduction</h4>Coronary artery bypass grafting (CABG) is a standard treatment for coronary artery disease, particularly in patients with multivessel disease. Connecting the saphenous vein graft (SVG) to the right internal mammary artery (RIMA) instead of the aorta has been proposed as an alternative approach to minimise aortic manipulation and potentially improve graft patency. This study aims to determine whether the RIMA-SVG technique is non-inferior to the conventional Aorta (Ao)-SVG approach in terms of 1-year graft patency, while also comparing perioperative complications and short-term clinical outcomes.<h4>Methods and analysis</h4>This non-inferiority, single-centre, prospective, double-blind, randomised clinical trial will enrol 300 patients undergoing CABG. Participants will","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-06-04T00:15:33.651Z","creation":"2026-05-03T03:11:44.766Z"},"accession":"S-EPMC12481333","cross_references":{"pubmed":["41022447"],"doi":["10.1136/bmjopen-2025-104578"]}}