{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["25(1)"],"submitter":["Falchetto LMM"],"funding":["Deutsches Krebsforschungszentrum (DKFZ)"],"pubmed_abstract":["<h4>Background</h4>While the line of therapy (LOT) concept is crucial for clinical decision-making in oncology, the concept lacks a consensual understanding bearing the risk of miscommunication. This study examines physicians' understanding of LOT, its perceived relevance, and the events and actions that determine a change of LOT within German oncological networks.<h4>Methods</h4>Employing a snowball sampling approach, an anonymous online-administered survey was conducted among German physicians with oncological experience. Descriptive statistics and consensus metrics (Gini Mean Difference [GMD] and normalized entropy) were used to summarize the survey results and the relative agreement among the respondents, respectively.<h4>Results</h4>Sixty physicians completed the survey. The majority "],"journal":["BMC cancer"],"pagination":["1439"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12482237"],"repository":["biostudies-literature"],"pubmed_title":["Reviewing the lines of therapy-concept in cancer treatment: a survey study among physicians."],"pmcid":["PMC12482237"],"pubmed_authors":["Bender B","Schnorr I","Falchetto LMM","Andreas S","Erhard I","Berger-Thurmel K","Maier D","Vehreschild JJ","Schumann LLI"],"additional_accession":[]},"is_claimable":false,"name":"Reviewing the lines of therapy-concept in cancer treatment: a survey study among physicians.","description":"<h4>Background</h4>While the line of therapy (LOT) concept is crucial for clinical decision-making in oncology, the concept lacks a consensual understanding bearing the risk of miscommunication. This study examines physicians' understanding of LOT, its perceived relevance, and the events and actions that determine a change of LOT within German oncological networks.<h4>Methods</h4>Employing a snowball sampling approach, an anonymous online-administered survey was conducted among German physicians with oncological experience. Descriptive statistics and consensus metrics (Gini Mean Difference [GMD] and normalized entropy) were used to summarize the survey results and the relative agreement among the respondents, respectively.<h4>Results</h4>Sixty physicians completed the survey. The majority ","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-06-03T23:00:13.379Z","creation":"2026-05-02T03:12:04.797Z"},"accession":"S-EPMC12482237","cross_references":{"pubmed":["41023956"],"doi":["10.1186/s12885-025-14940-0"]}}