{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Gomez RJ"],"funding":["Fundação para a Ciência e a Tecnologia","Brazilian National Council for Scientific and Technology Development of Brazil","Fundação de Amparo à Pesquisa do Estado de São Paulo"],"pagination":["738"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12482374"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["25(1)"],"pubmed_abstract":["<h4>Aim</h4>We investigated the impact of abrupt interruption, imposed by COVID-19, and subsequent resumption of regular practice of a combined exercise training program on protein, renal profile, and physical functional capacity in physically active older adults before the pandemic.<h4>Methods</h4>Thirty-five volunteers (mean age 64.36 ± 19.43 years) participated, with data collected before the COVID-19 pandemic (PRE), 12 months after social isolation (PAN, detraining period), and 10 months after returning to regular exercise (POST).<h4>Results</h4>In the POST period, both older women (n = 26) and men (n = 9) exhibited higher serum levels of albumin and total protein (p < 0.0001 for albumin and total proteins in older women group; p = 0.0033 for albumin and p = 0.0002 for total proteins i"],"journal":["BMC geriatrics"],"pubmed_title":["Mitigation of detraining effects: physical activity improves protein profile and physical function of aged amid COVID-19."],"pmcid":["PMC12482374"],"funding_grant_id":["2019/14115-0","CEECINST/00077/2021","PQ-2 #305008/2022-6"],"pubmed_authors":["da Silva FC","Amirato GR","Ribeiro AP","Bachi ALL","Silva BR","Rossi M","Botelho AR","da Silva Nali LH","de Almeida MS","Furtado GE","Monteiro FR","Gomez RJ","do Amaral JB","Nardy A","Paixao V","de Paula Vieira R","Santos CAF"],"additional_accession":[]},"is_claimable":false,"name":"Mitigation of detraining effects: physical activity improves protein profile and physical function of aged amid COVID-19.","description":"<h4>Aim</h4>We investigated the impact of abrupt interruption, imposed by COVID-19, and subsequent resumption of regular practice of a combined exercise training program on protein, renal profile, and physical functional capacity in physically active older adults before the pandemic.<h4>Methods</h4>Thirty-five volunteers (mean age 64.36 ± 19.43 years) participated, with data collected before the COVID-19 pandemic (PRE), 12 months after social isolation (PAN, detraining period), and 10 months after returning to regular exercise (POST).<h4>Results</h4>In the POST period, both older women (n = 26) and men (n = 9) exhibited higher serum levels of albumin and total protein (p < 0.0001 for albumin and total proteins in older women group; p = 0.0033 for albumin and p = 0.0002 for total proteins i","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-06-04T01:33:04.633Z","creation":"2026-05-03T03:14:11.931Z"},"accession":"S-EPMC12482374","cross_references":{"pubmed":["41023877"],"doi":["10.1186/s12877-025-06347-0"]}}