biostudies-literatureUnknown27(8)Tomasoni D<h4>Aims</h4>To assess the prevalence, prognostic significance, and predictors of heart failure hospitalization (HFH) before and after tricuspid transcatheter edge-to-edge repair (T-TEER) in a large real-world cohort of patients with tricuspid regurgitation (TR).<h4>Methods and results</h4>Data from the European Registry of Transcatheter Repair for Tricuspid Regurgitation (EuroTR registry) were analysed. Among 1000 patients undergoing T-TEER for symptomatic TR, 361 (36.1%) had no HFH, 459 (45.9%) had one single HFH, and 180 (18.0%) had multiple HFH the year before T-TEER. Patients with any HFH had more severe heart failure compared with those without. Procedural success (residual TR ≤2) did not differ between patients with single, multiple, or no HFHs before T-TEER. Multivariable analysis European journal of heart failure1559-1569https://www.ebi.ac.uk/biostudies/studies/S-EPMC12482852biostudies-literatureHeart failure hospitalizations and clinical outcomes in patients undergoing tricuspid transcatheter edge-to-edge repair: Insights from EuroTR.PMC12482852Kassar MLapp HPfister RTarantini GRottbauer WCaneiro-Queija BFortmeier VRassaf TToggweiler SNovotny JZdanyte MDenti PGiannini CWild MGGoebel BKoell BBoekstegers PRousse NSalomon CEcharte JCEuroTR InvestigatorsRosch Svon Bardeleben RSVan Belle EBaldus SFrey NGrapsa JStolz LBrunner SKister TLudwig SKresoja KPPraz FPanza APezzola ESchlegel PWeckbach LTMazzola MKessler MLauten PTomasoni DLuedike PKonstandin MHSchreieck JThiele HRudolph FPancaldi EAghezzaf SAchouh PBesler CDe Carlo MBerrebi AKraus MJKalbacher DSchindhelm FZiegler LIliadis CRuck ABarreiro-Perez MArturi FEstevez-Loureiro RFelbel DMetra MPauschinger CAdamo MPuscas TGoldschmied Avon Stein JSticchi AVincent FBranca LGercek MHausleiter JPatterson TMaisano FLurz PRudolph VMahabadi AAMasiero GGeisler TKaram NSchneider LMfalseHeart failure hospitalizations and clinical outcomes in patients undergoing tricuspid transcatheter edge-to-edge repair: Insights from EuroTR.<h4>Aims</h4>To assess the prevalence, prognostic significance, and predictors of heart failure hospitalization (HFH) before and after tricuspid transcatheter edge-to-edge repair (T-TEER) in a large real-world cohort of patients with tricuspid regurgitation (TR).<h4>Methods and results</h4>Data from the European Registry of Transcatheter Repair for Tricuspid Regurgitation (EuroTR registry) were analysed. Among 1000 patients undergoing T-TEER for symptomatic TR, 361 (36.1%) had no HFH, 459 (45.9%) had one single HFH, and 180 (18.0%) had multiple HFH the year before T-TEER. Patients with any HFH had more severe heart failure compared with those without. Procedural success (residual TR ≤2) did not differ between patients with single, multiple, or no HFHs before T-TEER. Multivariable analysis 2025-01-01T00:00:00Z2025 Aug2026-06-04T01:43:17.147Z2026-05-04T03:13:21.152ZS-EPMC124828524067899210.1002/ejhf.3757