biostudies-literatureUnknown25(1)Abidin ZU<h4>Background</h4>The COVID-19 pandemic disproportionately affected various demographics and regions in the United States. Understanding disparities in COVID-19 mortality is essential for promoting health equity and guiding future responses.<h4>Objective</h4>To examine demographic and regional disparities in age-adjusted and proportionate COVID-19 mortality in the US from 2020 to 2023.<h4>Design, setting, and participants</h4>In this repeated cross-sectional study, data from the Centers for Disease Control and Prevention Wide-ranging Online Data for Epidemiologic Research (CDC WONDER) multiple causes of death database were used to analyze death certificates from 2020 to 2023 for COVID-19-related mortality among persons aged ≥ 15 years in the U.S.<h4>Main outcome measures</h4>Age-adjusted BMC public health3257https://www.ebi.ac.uk/biostudies/studies/S-EPMC12487207biostudies-literatureDisparities in COVID-19 mortality in the United States, 2020-2023.PMC12487207Gupta JSThirumalareddy JAbidin ZUAbdul Jabbar ABfalseDisparities in COVID-19 mortality in the United States, 2020-2023.<h4>Background</h4>The COVID-19 pandemic disproportionately affected various demographics and regions in the United States. Understanding disparities in COVID-19 mortality is essential for promoting health equity and guiding future responses.<h4>Objective</h4>To examine demographic and regional disparities in age-adjusted and proportionate COVID-19 mortality in the US from 2020 to 2023.<h4>Design, setting, and participants</h4>In this repeated cross-sectional study, data from the Centers for Disease Control and Prevention Wide-ranging Online Data for Epidemiologic Research (CDC WONDER) multiple causes of death database were used to analyze death certificates from 2020 to 2023 for COVID-19-related mortality among persons aged ≥ 15 years in the U.S.<h4>Main outcome measures</h4>Age-adjusted 2025-01-01T00:00:00Z2025 Oct2026-06-04T02:26:53.782Z2026-05-04T03:13:17.58ZS-EPMC124872074103476610.1186/s12889-025-24530-1