biostudies-literatureDing BJiangsu Province Medical Research General ProjectSuzhou Major Disease Multicentre Clinical Research ProjectNational Key Research and Development Program of China34261https://www.ebi.ac.uk/biostudies/studies/S-EPMC12488935biostudies-literatureUnknown15(1)Preoperative anxiety is common among adults undergoing elective surgery and has been associated with adverse clinical outcomes. This study evaluated the effectiveness of music intervention in reducing preoperative anxiety compared with standard care. In this randomized controlled trial, 104 women scheduled for elective gynecological surgery with elevated anxiety levels (State-Trait Anxiety Inventory-State scale ≥ 39) were enrolled. Participants were randomized in a 1:1 ratio to receive either the two sessions of preoperative music intervention (one on the eve of surgery and another in the anesthesia preparation room) or a control condition consisting of headphones without music. The primary outcome was the change in anxiety between post-intervention on the day of surgery (T3) and baseline Scientific reportsEffect of music intervention on preoperative anxiety, a randomised clinical study.PMC124889352023YFC3603503H2023019DZXYJ202401Shen LQian JYan JShan XDing BDu CPan TZhang YJi FDeng MfalseEffect of music intervention on preoperative anxiety, a randomised clinical study.Preoperative anxiety is common among adults undergoing elective surgery and has been associated with adverse clinical outcomes. This study evaluated the effectiveness of music intervention in reducing preoperative anxiety compared with standard care. In this randomized controlled trial, 104 women scheduled for elective gynecological surgery with elevated anxiety levels (State-Trait Anxiety Inventory-State scale ≥ 39) were enrolled. Participants were randomized in a 1:1 ratio to receive either the two sessions of preoperative music intervention (one on the eve of surgery and another in the anesthesia preparation room) or a control condition consisting of headphones without music. The primary outcome was the change in anxiety between post-intervention on the day of surgery (T3) and baseline 2025-01-01T00:00:00Z2025 Oct2026-05-03T03:23:33.504Z2026-05-03T03:14:12.875ZS-EPMC124889354103437110.1038/s41598-025-16413-7