{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Poetzsch SN"],"funding":["Foundation for Research in Science and the Humanities"],"pagination":["2086-2095"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12489288"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["17(10)"],"pubmed_abstract":["Cannabis sativa L. constituents, such as cannabinoids, terpenes, flavonoids, and other secondary metabolites, determine the plant's (medicinal) effects and properties in a complex interplay, a phenomenon known as the entourage effect. However, environmental influences like cultivation method, soil, light, and climate might also influence the plant's chemical composition-and thus its therapeutic profile. Much like in viticulture, the concept of a \"cannabis terroir\" might play an important role in determining the plant's chemical phenotype. The aim of this study was therefore to make these complex properties analytically accessible and develop a comprehensive metabolomics workflow using gas chromatography-high-resolution mass spectrometry (GC-HRMS) and liquid chromatography-high-resolution t"],"journal":["Drug testing and analysis"],"pubmed_title":["Toward a Cannabis Terroir: Untargeted Metabolomic Profiling of Authentic Samples Using Gas Chromatography-High-Resolution Mass Spectrometry (GC-HRMS) and Liquid Chromatography-High-Resolution Tandem Mass Spectrometry (LC-HRMS/MS)."],"pmcid":["PMC12489288"],"funding_grant_id":["STWF-22-012","STWF‐22‐012"],"pubmed_authors":["Poetzsch M","Kraemer T","Steuer AE","Poetzsch SN"],"additional_accession":[]},"is_claimable":false,"name":"Toward a Cannabis Terroir: Untargeted Metabolomic Profiling of Authentic Samples Using Gas Chromatography-High-Resolution Mass Spectrometry (GC-HRMS) and Liquid Chromatography-High-Resolution Tandem Mass Spectrometry (LC-HRMS/MS).","description":"Cannabis sativa L. constituents, such as cannabinoids, terpenes, flavonoids, and other secondary metabolites, determine the plant's (medicinal) effects and properties in a complex interplay, a phenomenon known as the entourage effect. However, environmental influences like cultivation method, soil, light, and climate might also influence the plant's chemical composition-and thus its therapeutic profile. Much like in viticulture, the concept of a \"cannabis terroir\" might play an important role in determining the plant's chemical phenotype. The aim of this study was therefore to make these complex properties analytically accessible and develop a comprehensive metabolomics workflow using gas chromatography-high-resolution mass spectrometry (GC-HRMS) and liquid chromatography-high-resolution t","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Oct","modification":"2026-06-04T00:38:20.625Z","creation":"2026-05-03T03:13:10.943Z"},"accession":"S-EPMC12489288","cross_references":{"pubmed":["40589191"],"doi":["10.1002/dta.3922"]}}