{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["22(1)"],"submitter":["Deng H"],"pubmed_abstract":["<h4>Background</h4>Caffeine (CAF) and taurine (TAU) have each demonstrated ergogenic effects across physical and cognitive domains. Often co-formulated in commercial energy drinks, they are widely regarded as the two principal bioactive compounds. However, findings regarding their combined efficacy remain inconclusive. This systematic review and Bayesian network meta-analysis aimed to quantify the individual and combined effects of CAF and TAU on physical capacity, cognitive function, and physiological responses, with a focus on identifying potential synergistic or antagonistic interactions.<h4>Methods</h4>Cochrane Library, PubMed, SciELO, SportsDiscus-EBSCO and Web of Science were searched through 25 July 2025. The pooled effect of each outcome was summarized using SMD (Hedge's g) by Baye"],"journal":["Journal of the International Society of Sports Nutrition"],"pagination":["2566371"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12490369"],"repository":["biostudies-literature"],"pubmed_title":["Caffeine and taurine: a systematic review and network meta-analysis of their individual and combined effects on physical capacity, cognitive function, and physiological markers."],"pmcid":["PMC12490369"],"pubmed_authors":["Bin Naharudin MN","Fan X","Liu P","Deng H","Wang L"],"additional_accession":[]},"is_claimable":false,"name":"Caffeine and taurine: a systematic review and network meta-analysis of their individual and combined effects on physical capacity, cognitive function, and physiological markers.","description":"<h4>Background</h4>Caffeine (CAF) and taurine (TAU) have each demonstrated ergogenic effects across physical and cognitive domains. Often co-formulated in commercial energy drinks, they are widely regarded as the two principal bioactive compounds. However, findings regarding their combined efficacy remain inconclusive. This systematic review and Bayesian network meta-analysis aimed to quantify the individual and combined effects of CAF and TAU on physical capacity, cognitive function, and physiological responses, with a focus on identifying potential synergistic or antagonistic interactions.<h4>Methods</h4>Cochrane Library, PubMed, SciELO, SportsDiscus-EBSCO and Web of Science were searched through 25 July 2025. The pooled effect of each outcome was summarized using SMD (Hedge's g) by Baye","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Dec","modification":"2026-06-04T00:26:52.475Z","creation":"2026-05-03T03:12:30.89Z"},"accession":"S-EPMC12490369","cross_references":{"pubmed":["41032459"],"doi":["10.1080/15502783.2025.2566371"]}}