{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["18(4)"],"submitter":["Garrett A"],"funding":["National Institute of Neurological Disorders and Stroke","NICHD NIH HHS","NIDDK NIH HHS","National Institute of Diabetes and Digestive and Kidney Diseases","NIGMS NIH HHS"],"pubmed_abstract":["<i>Objective.</i>The peripheral nervous system (PNS) connects the central nervous system with the rest of the body to regulate many physiological functions and is therapeutically targeted to treat diseases such as epilepsy, depression, intestinal dysmotility, chronic pain, and more. However, we still lack understanding of PNS innervation in most organs because the large span, diffuse nature, and small terminal nerve bundle fibers have precluded whole-organism, high resolution mapping of the PNS. We sought to produce a comprehensive peripheral nerve atlas for use in future interrogation of neural circuitry and selection of targets for neuromodulation.<i>Approach.</i>We used diffusion tensor magnetic resonance imaging (DT-MRI) with high-speed compressed sensing to generate a tractogram of th"],"journal":["Journal of neural engineering"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12490744"],"repository":["biostudies-literature"],"pubmed_title":["Mapping the peripheral nervous system in the whole mouse via compressed sensing tractography."],"pmcid":["PMC12490744"],"funding_grant_id":["NIH R35GM122465","R35 GM122465","R01 DK119795","DK119795","R01 HD090050"],"pubmed_authors":["Wang N","McKey J","Cofer G","Anderson RB","Rakhilin N","Johnson GA","Capel B","Garrett A","Shen X"],"additional_accession":[]},"is_claimable":false,"name":"Mapping the peripheral nervous system in the whole mouse via compressed sensing tractography.","description":"<i>Objective.</i>The peripheral nervous system (PNS) connects the central nervous system with the rest of the body to regulate many physiological functions and is therapeutically targeted to treat diseases such as epilepsy, depression, intestinal dysmotility, chronic pain, and more. However, we still lack understanding of PNS innervation in most organs because the large span, diffuse nature, and small terminal nerve bundle fibers have precluded whole-organism, high resolution mapping of the PNS. We sought to produce a comprehensive peripheral nerve atlas for use in future interrogation of neural circuitry and selection of targets for neuromodulation.<i>Approach.</i>We used diffusion tensor magnetic resonance imaging (DT-MRI) with high-speed compressed sensing to generate a tractogram of th","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Jun","modification":"2026-06-04T02:28:05.409Z","creation":"2026-05-04T03:13:26.922Z"},"accession":"S-EPMC12490744","cross_references":{"pubmed":["33979784"],"doi":["10.1088/1741-2552/ac0089"]}}