biostudies-literatureXiong STop Talent Support Program for young and middle-aged people of Wuxi Health CommitteeWuxi Municipal Bureau on Science and TechnologyWuxi Taihu Lake Talent PlanNatural Science Foundation of Jiangsu Province746https://www.ebi.ac.uk/biostudies/studies/S-EPMC12492913biostudies-literatureUnknown25(1)<h4>Background</h4>Owing to the absence of straightforward and scientifically validated screening and evaluation tools for the timely identification, diagnosis, and treatment of critical influenza A infection in children, this study aimed to construct an effective model for the early identification of patients at high risk of progressing to critical influenza A infection.<h4>Methods</h4>The prediction model was developed using the registration data of children diagnosed with influenza A who were admitted to Wuxi Children's Hospital, the Children's Hospital Affiliated to Soochow University and the Children's Hospital Affiliated to Fudan University. Patients were randomly divided into a training group and a validation group at a 7:3 ratio. A logistic regression model was established based onBMC pediatricsA simple, rapid, and cost-effective model for predicting critical influenza a infection in children: a multicentre, retrospective cohort study.PMC12492913BK20230189K20221033DJTD202304BJ2023089Zhu PQian JJiang LGuo YChen WXiong SBai ZWang YLi LfalseA simple, rapid, and cost-effective model for predicting critical influenza a infection in children: a multicentre, retrospective cohort study.<h4>Background</h4>Owing to the absence of straightforward and scientifically validated screening and evaluation tools for the timely identification, diagnosis, and treatment of critical influenza A infection in children, this study aimed to construct an effective model for the early identification of patients at high risk of progressing to critical influenza A infection.<h4>Methods</h4>The prediction model was developed using the registration data of children diagnosed with influenza A who were admitted to Wuxi Children's Hospital, the Children's Hospital Affiliated to Soochow University and the Children's Hospital Affiliated to Fudan University. Patients were randomly divided into a training group and a validation group at a 7:3 ratio. A logistic regression model was established based on2025-01-01T00:00:00Z2025 Oct2026-06-04T02:34:21.388Z2026-05-31T03:06:29.47ZS-EPMC124929134103929610.1186/s12887-025-06085-7