{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["6(1)"],"submitter":["Mizuki Y"],"pubmed_abstract":["<h4>Objective</h4>To investigate seasonal trends in the onset of Vogt-Koyanagi-Harada (VKH) disease in Japan and evaluate the influence of the coronavirus disease 2019 (COVID-19) pandemic, including severe cases and vaccination campaigns, on disease onset.<h4>Design</h4>A retrospective cohort study using clinical records and public health data.<h4>Participants</h4>A total of 320 Japanese VKH patients with a known month of onset who were initially treated at Yokohama City University Hospital between April 2007 and March 2024.<h4>Methods</h4>The monthly distribution of VKH onset cases was assessed using the Roger test to determine seasonality before and after the COVID-19 pandemic. Severe COVID-19 case data (April 2020 to March 2024) were obtained from government sources. The COVID-19 vaccin"],"journal":["Ophthalmology science"],"pagination":["100902"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12494803"],"repository":["biostudies-literature"],"pubmed_title":["Seasonal Variations of Vogt-Koyanagi-Harada Disease in Japan: A Study on Long-Term Trends and the Influence of Coronavirus Disease 2019 (COVID-19)."],"pmcid":["PMC12494803"],"pubmed_authors":["Yamamoto K","Ohno S","Okada H","Sakono T","Mizuki Y","Horita N","Kawagoe T","Mizuki N","Ishihara M","Yamada N","Meguro A"],"additional_accession":[]},"is_claimable":false,"name":"Seasonal Variations of Vogt-Koyanagi-Harada Disease in Japan: A Study on Long-Term Trends and the Influence of Coronavirus Disease 2019 (COVID-19).","description":"<h4>Objective</h4>To investigate seasonal trends in the onset of Vogt-Koyanagi-Harada (VKH) disease in Japan and evaluate the influence of the coronavirus disease 2019 (COVID-19) pandemic, including severe cases and vaccination campaigns, on disease onset.<h4>Design</h4>A retrospective cohort study using clinical records and public health data.<h4>Participants</h4>A total of 320 Japanese VKH patients with a known month of onset who were initially treated at Yokohama City University Hospital between April 2007 and March 2024.<h4>Methods</h4>The monthly distribution of VKH onset cases was assessed using the Roger test to determine seasonality before and after the COVID-19 pandemic. Severe COVID-19 case data (April 2020 to March 2024) were obtained from government sources. The COVID-19 vaccin","dates":{"release":"2026-01-01T00:00:00Z","publication":"2026 Jan","modification":"2026-06-15T06:09:36.821Z","creation":"2026-06-15T03:08:42.698Z"},"accession":"S-EPMC12494803","cross_references":{"pubmed":["41049114"],"doi":["10.1016/j.xops.2025.100902"]}}