{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["16(1)"],"submitter":["Yuan Y"],"pubmed_abstract":["<h4>Objective</h4>The purpose of our research was to investigate the clinical significance of lncRNA VIM anti-sense 1 (VIM-AS1) and to elucidate its cellular functions in breast cancer patients.<h4>Methods</h4>A cohort of one hundred and twenty-one individuals diagnosed with breast cancer and 95 healthy volunteers were recruited for this study. Relative abundances of VIM-AS1 were detected through quantitative real-time polymerase chain reaction (qRT-PCR). Receiver operating characteristic (ROC) was employed for evaluating the diagnosis potential of VIM-AS1. Kaplan-Meier method and Cox regression analysis was performed to further examine the prognostic performance of VIM-AS1. The cellular events of VIM-AS1 were assessed via CCK-8 and Transwell assay. The target interaction of VIM-AS1 and mi"],"journal":["Discover oncology"],"pagination":["1807"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12495003"],"repository":["biostudies-literature"],"pubmed_title":["LncRNA VIM-AS1 is a potential prognostic biomarker and effects on tumor cellular behaviors in breast cancer via impairing miR-29a-3p."],"pmcid":["PMC12495003"],"pubmed_authors":["Wei M","Kong L","Zhang H","Yuan Q","Li P","Bian W","Yuan Y"],"additional_accession":[]},"is_claimable":false,"name":"LncRNA VIM-AS1 is a potential prognostic biomarker and effects on tumor cellular behaviors in breast cancer via impairing miR-29a-3p.","description":"<h4>Objective</h4>The purpose of our research was to investigate the clinical significance of lncRNA VIM anti-sense 1 (VIM-AS1) and to elucidate its cellular functions in breast cancer patients.<h4>Methods</h4>A cohort of one hundred and twenty-one individuals diagnosed with breast cancer and 95 healthy volunteers were recruited for this study. Relative abundances of VIM-AS1 were detected through quantitative real-time polymerase chain reaction (qRT-PCR). Receiver operating characteristic (ROC) was employed for evaluating the diagnosis potential of VIM-AS1. Kaplan-Meier method and Cox regression analysis was performed to further examine the prognostic performance of VIM-AS1. The cellular events of VIM-AS1 were assessed via CCK-8 and Transwell assay. The target interaction of VIM-AS1 and mi","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Oct","modification":"2026-05-31T03:16:15.799Z","creation":"2026-05-31T03:06:42.246Z"},"accession":"S-EPMC12495003","cross_references":{"pubmed":["41042406"],"doi":["10.1007/s12672-025-03568-y"]}}