<HashMap><database>biostudies-literature</database><scores/><additional><omics_type>Unknown</omics_type><volume>9(10)</volume><submitter>Bellina G</submitter><pubmed_abstract>&lt;h4>Background&lt;/h4>Mitral transcatheter edge-to-edge repair (M-TEER) is commonly performed in elderly patients with severe mitral regurgitation (MR) who are deemed high-risk for surgery. However, its application in younger patients remains limited.&lt;h4>Case summary&lt;/h4>We present the case of a 45-year-old male with a history of mitral valve prolapse, who developed severe MR due to chordal rupture. Surgical mitral valve repair was not considered feasible, and the patient successfully underwent M-TEER with implantation of two MitraClips XTW (Abbott Medical, USA), resulting in mild residual regurgitation and a mean mitral valve gradient of 5 mmHg.&lt;h4>Discussion&lt;/h4>This case highlights the potential role of M-TEER in selected young patients, expanding its indications beyond traditional cohorts</pubmed_abstract><journal>European heart journal. Case reports</journal><pagination>ytaf464</pagination><full_dataset_link>https://www.ebi.ac.uk/biostudies/studies/S-EPMC12495034</full_dataset_link><repository>biostudies-literature</repository><pubmed_title>Successful mitral-transcatheter edge to edge repair in a young patient with severe primary mitral regurgitation unsuitable for surgery: a case report.</pubmed_title><pmcid>PMC12495034</pmcid><pubmed_authors>Scandura S</pubmed_authors><pubmed_authors>Capodanno D</pubmed_authors><pubmed_authors>Bellina G</pubmed_authors><pubmed_authors>Grasso C</pubmed_authors><pubmed_authors>Mazzone PM</pubmed_authors></additional><is_claimable>false</is_claimable><name>Successful mitral-transcatheter edge to edge repair in a young patient with severe primary mitral regurgitation unsuitable for surgery: a case report.</name><description>&lt;h4>Background&lt;/h4>Mitral transcatheter edge-to-edge repair (M-TEER) is commonly performed in elderly patients with severe mitral regurgitation (MR) who are deemed high-risk for surgery. However, its application in younger patients remains limited.&lt;h4>Case summary&lt;/h4>We present the case of a 45-year-old male with a history of mitral valve prolapse, who developed severe MR due to chordal rupture. Surgical mitral valve repair was not considered feasible, and the patient successfully underwent M-TEER with implantation of two MitraClips XTW (Abbott Medical, USA), resulting in mild residual regurgitation and a mean mitral valve gradient of 5 mmHg.&lt;h4>Discussion&lt;/h4>This case highlights the potential role of M-TEER in selected young patients, expanding its indications beyond traditional cohorts</description><dates><release>2025-01-01T00:00:00Z</release><publication>2025 Oct</publication><modification>2026-05-31T03:15:13.958Z</modification><creation>2026-05-31T03:07:05.561Z</creation></dates><accession>S-EPMC12495034</accession><cross_references><pubmed>41050529</pubmed><doi>10.1093/ehjcr/ytaf464</doi></cross_references></HashMap>