biostudies-literatureUnknown81(Pt 10)Kingsley NBThe title compound C₁₅H₈BrF₆N, was prepared by a condensation reaction of 2-bromo-benzaldehyde and 3,5-bis-(tri-fluoro-meth-yl)aniline in the presence of anhydrous magnesium sulfate. The compound readily crystallizes from a concentrated hexa-nes solution in high yield. The imine bond is nearly planar with the 2-bromo-phenyl group, while the <i>N</i>-(3,5-bis-(tri-fluoro-meth-yl)phenyl moiety is significantly twisted from the imine group [49.61 (5)°]. The crystal packing involves short inter-molecular C-H⋯Br contacts linking zigzag ribbons flanked by fluorous layers.Acta crystallographica. Section E, Crystallographic communications916-919https://www.ebi.ac.uk/biostudies/studies/S-EPMC12498049biostudies-literatureSynthesis and crystal structure of (&lt;i&gt;E&lt;/i&gt;)-&lt;i&gt;N&lt;/i&gt;-[(2-bromo-phen-yl)methyl-idene]-3,5-bis-(tri-fluoro-meth-yl)aniline.PMC12498049Doyon TJJanzen DEKingsley NBfalseSynthesis and crystal structure of (&lt;i&gt;E&lt;/i&gt;)-&lt;i&gt;N&lt;/i&gt;-[(2-bromo-phen-yl)methyl-idene]-3,5-bis-(tri-fluoro-meth-yl)aniline.The title compound C₁₅H₈BrF₆N, was prepared by a condensation reaction of 2-bromo-benzaldehyde and 3,5-bis-(tri-fluoro-meth-yl)aniline in the presence of anhydrous magnesium sulfate. The compound readily crystallizes from a concentrated hexa-nes solution in high yield. The imine bond is nearly planar with the 2-bromo-phenyl group, while the <i>N</i>-(3,5-bis-(tri-fluoro-meth-yl)phenyl moiety is significantly twisted from the imine group [49.61 (5)°]. The crystal packing involves short inter-molecular C-H⋯Br contacts linking zigzag ribbons flanked by fluorous layers.2025-01-01T00:00:00Z2025 Oct2026-05-06T03:19:05.894Z2026-05-06T03:13:05.339ZS-EPMC124980494105932310.1107/S2056989025007650