{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Main MU"],"funding":["Heriot-Watt University","James-Watt Scholarship Scheme","EPSRC","Office of Science","Centre for Doctoral Training in Critical Resource Catalysis"],"pagination":["e02113"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12498068"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["31(55)"],"pubmed_abstract":["BODIPY-functionalized host molecules have been used as effective visible-light photosensitizers in the conversion of α-terpinene to ascaridole in the presence of molecular oxygen. Host-guest interactions enhance the effective local concentration of the substrate and singlet oxygen generated by the photosensitizing host. This results in up to a 28-fold increase in the rate of conversion depending on the host employed. A tetramethyl BODIPY analogue, in which guest access to the host cavity is blocked, was also employed to confirm that the cavities do indeed enhance substrate turnover. Whilst the latter photocatalyst is more efficient due to the suppression of nonradiative relaxation pathways associated with rotation of the meso-phenyl substituent, the rate enhancement induced by host-guest b"],"journal":["Chemistry (Weinheim an der Bergstrasse, Germany)"],"pubmed_title":["Host Cavities Enhance the Photocatalytic Conversion of α-Terpinene to Ascaridole Under Visible-Light Irradiation."],"pmcid":["PMC12498068"],"funding_grant_id":["DE-AC02-05CH11231","EP/V006746/1","EP/T021675/1"],"pubmed_authors":["McCormick McPherson LJ","Teat SJ","Jones CMS","Vilela F","Taylor D","Marques-Hueso J","Tobin JM","Paterson MJ","Dalgarno SJ","Amicosante L","Main MU","Ellis D"],"additional_accession":[]},"is_claimable":false,"name":"Host Cavities Enhance the Photocatalytic Conversion of α-Terpinene to Ascaridole Under Visible-Light Irradiation.","description":"BODIPY-functionalized host molecules have been used as effective visible-light photosensitizers in the conversion of α-terpinene to ascaridole in the presence of molecular oxygen. Host-guest interactions enhance the effective local concentration of the substrate and singlet oxygen generated by the photosensitizing host. This results in up to a 28-fold increase in the rate of conversion depending on the host employed. A tetramethyl BODIPY analogue, in which guest access to the host cavity is blocked, was also employed to confirm that the cavities do indeed enhance substrate turnover. Whilst the latter photocatalyst is more efficient due to the suppression of nonradiative relaxation pathways associated with rotation of the meso-phenyl substituent, the rate enhancement induced by host-guest b","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Oct","modification":"2026-06-04T04:49:23.932Z","creation":"2026-05-05T03:12:38.256Z"},"accession":"S-EPMC12498068","cross_references":{"pubmed":["40891547"],"doi":["10.1002/chem.202502113"]}}