biostudies-literatureCassedy ANational Center for Advancing Translational SciencesArthritis FoundationNational Eye InstituteNEI NIH HHSRheumatology Research FoundationChildhood Arthritis and Rheumatology Research AllianceKnights Templar Eye FoundationNIAMS NIH HHS355-363https://www.ebi.ac.uk/biostudies/studies/S-EPMC12498490biostudies-literatureUnknown74(3)<h4>Objective</h4>The Effects of Youngsters' Eyesight on Quality of Life (EYE-Q) questionnaire measures vision-related functioning (VRF) and vision-related quality of life (VRQoL) in children with uveitis. Our aim was to revise the alpha version of the EYE-Q to refine VRF and VRQoL subscales and to assess the validity of the EYE-Q.<h4>Methods</h4>Children with juvenile idiopathic arthritis (JIA), JIA-associated uveitis, and other noninfectious uveitis were enrolled. Patients and parents completed the EYE-Q, Pediatric Quality of Life Inventory (overall quality of life), and Childhood Health Assessment Questionnaire (physical functioning). The development site completed the alpha version of the EYE-Q, and the composite sites completed the beta version. We compared item-subscale correlations,Arthritis care & researchAssessing the Validity and Reliability of the Effects of Youngsters' Eyesight on Quality of Life Questionnaire Among Children With Uveitis.PMC12498490P30 AR076316R01‐EY‐030521K23 EY021760L40 EY019856K23‐EY‐021760UL1‐TR‐000077Engelhard GHolland GNWalker AALipscomb JMcDonald JPrahalad SMwase NDrews-Botsch CHennard TMcCracken CAndringa JLambert SRCooper AMStahl EAngeles-Han STUtz VMYeh SCassedy AMcCurdy DKAltaye MJenkins KfalseAssessing the Validity and Reliability of the Effects of Youngsters' Eyesight on Quality of Life Questionnaire Among Children With Uveitis.<h4>Objective</h4>The Effects of Youngsters' Eyesight on Quality of Life (EYE-Q) questionnaire measures vision-related functioning (VRF) and vision-related quality of life (VRQoL) in children with uveitis. Our aim was to revise the alpha version of the EYE-Q to refine VRF and VRQoL subscales and to assess the validity of the EYE-Q.<h4>Methods</h4>Children with juvenile idiopathic arthritis (JIA), JIA-associated uveitis, and other noninfectious uveitis were enrolled. Patients and parents completed the EYE-Q, Pediatric Quality of Life Inventory (overall quality of life), and Childhood Health Assessment Questionnaire (physical functioning). The development site completed the alpha version of the EYE-Q, and the composite sites completed the beta version. We compared item-subscale correlations,2022-01-01T00:00:00Z2022 Mar2026-06-04T04:49:54.255Z2026-05-05T03:12:42.178ZS-EPMC124984903308584910.1002/acr.24491