{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["27(10)"],"submitter":["Hamamoto H"],"pubmed_abstract":["<h4>Aim</h4>Laparoscopic low anterior resection is widely used for treating rectal cancer; however, postoperative complications frequently result in a marked deterioration in the patients' quality of life (QOL). This study aimed to investigate the trajectory of QOL recovery and identify the risk factors affecting QOL in patients undergoing laparoscopic surgery for very low rectal cancer.<h4>Method</h4>This prospective, multi-institutional, single-arm, phase-II trial examined the outcomes of laparoscopic surgery in patients with very low rectal cancer (<5 cm from the anus). The Short Form 36 Health Survey questionnaire was used to assess QOL preoperatively and at 3 and 6 months and 1, 2 and 3 years postoperatively. Univariate and multivariate logistic regression analyses were performed to i"],"journal":["Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland"],"pagination":["e70255"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12501488"],"repository":["biostudies-literature"],"pubmed_title":["Quality of life after laparoscopic surgery for very low rectal cancer: A sub-analysis of the ultimate trial."],"pmcid":["PMC12501488"],"pubmed_authors":["Saito S","Otsuka K","Toiyama Y","Ito M","Maruyama S","Naitoh T","Watanabe J","Watanabe M","Ohnuma S","Inomata M","Shiomi A","Hirano Y","Kuriu Y","Yamamoto M","Yoshioka S","Sakamoto K","Yamamoto S","Shiozawa M","Nagano H","Yoshimitsu M","Hamamoto H","Hayama T","Inoue Y","Suwa H","Matsuhashi N","Hamada M","Tsuruta A","Suzuki M","Murata K","Nishigori H","Nagai S","Inada R","Uemura M","Horie H","Takahashi Y","Ueda K","Yamaguchi S","Ultimate Trial Group in Japan Society of Laparoscopic Colorectal Surgery","Miyakura Y","Hida K","Mori S","Tanaka K","Ozawa H","Misumi T","Tei M","Fukunaga Y","Okamura S","Tsukada Y","Nonaka T","Kanemitsu Y","Hotchi M","Makizumi R"],"additional_accession":[]},"is_claimable":false,"name":"Quality of life after laparoscopic surgery for very low rectal cancer: A sub-analysis of the ultimate trial.","description":"<h4>Aim</h4>Laparoscopic low anterior resection is widely used for treating rectal cancer; however, postoperative complications frequently result in a marked deterioration in the patients' quality of life (QOL). This study aimed to investigate the trajectory of QOL recovery and identify the risk factors affecting QOL in patients undergoing laparoscopic surgery for very low rectal cancer.<h4>Method</h4>This prospective, multi-institutional, single-arm, phase-II trial examined the outcomes of laparoscopic surgery in patients with very low rectal cancer (<5 cm from the anus). The Short Form 36 Health Survey questionnaire was used to assess QOL preoperatively and at 3 and 6 months and 1, 2 and 3 years postoperatively. Univariate and multivariate logistic regression analyses were performed to i","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Oct","modification":"2026-06-04T06:52:51.855Z","creation":"2026-05-06T03:13:30.577Z"},"accession":"S-EPMC12501488","cross_references":{"pubmed":["41054197"],"doi":["10.1111/codi.70255"]}}