{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13(10)"],"submitter":["Halperin AV"],"pubmed_abstract":["Bloodstream infections cause great mortality and morbidity. Real-time microbiological information has been shown to have an impact on prognosis when combined with an antimicrobial stewardship (AMS) program. dRAST is a rapid commercial antimicrobial susceptibility testing (AST) system based on real-time microscopy. The primary outcome of this trial was to compare positive blood culture's time-to-result (TTR), defined as time from Gram stain to AST report, between dRAST and our standard of care in a real-life clinical setting. Secondary outcomes included microbiological concordance, time to antimicrobial stewardship recommendation (TAMS), and time to change antimicrobial prescription (TCAP) in agreement with AMS recommendation. We performed a prospective, open-label, randomized (1:1) diagnos"],"journal":["Microbiology spectrum"],"pagination":["e0028825"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12502579"],"repository":["biostudies-literature"],"pubmed_title":["Randomized controlled diagnostic trial to assess dRAST time to result and its utility for antimicrobial stewardship recommendation in bacteremic patients."],"pmcid":["PMC12502579"],"pubmed_authors":["Escudero R","Cardenas-Isasi MJ","Garcia-Castillo M","Canton R","Halperin AV","Cobo J","Gioia F","Sanchez-Diaz AM"],"additional_accession":[]},"is_claimable":false,"name":"Randomized controlled diagnostic trial to assess dRAST time to result and its utility for antimicrobial stewardship recommendation in bacteremic patients.","description":"Bloodstream infections cause great mortality and morbidity. Real-time microbiological information has been shown to have an impact on prognosis when combined with an antimicrobial stewardship (AMS) program. dRAST is a rapid commercial antimicrobial susceptibility testing (AST) system based on real-time microscopy. The primary outcome of this trial was to compare positive blood culture's time-to-result (TTR), defined as time from Gram stain to AST report, between dRAST and our standard of care in a real-life clinical setting. Secondary outcomes included microbiological concordance, time to antimicrobial stewardship recommendation (TAMS), and time to change antimicrobial prescription (TCAP) in agreement with AMS recommendation. We performed a prospective, open-label, randomized (1:1) diagnos","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Oct","modification":"2026-06-04T06:20:56.927Z","creation":"2026-05-06T03:13:20.402Z"},"accession":"S-EPMC12502579","cross_references":{"pubmed":["40815165"],"doi":["10.1128/spectrum.00288-25"]}}