biostudies-literatureUnknownWang W<h4>Study design</h4>Monocentric, retrospective, cross-sectional study.<h4>Objective</h4>To investigate the age-related normative values of sagittal parameters and establish their relationships in asymptomatic community-dwelling adults aged over 50.<h4>Background context</h4>Degenerative changes in the spine with aging alter the sagittal balance, causing spine pathologies. However, there was a lack of comprehensive study on age-related normative values of sagittal alignment and their relationship during degenerative evolution.<h4>Methods</h4>Among a total of 1,370 volunteers, 701 asymptomatic volunteers were recruited. Participants underwent a lateral X-ray, and sagittal parameters were assessed using a customized computer application.<h4>Results</h4>Age showed a stronger correlation with Spinehttps://www.ebi.ac.uk/biostudies/studies/S-EPMC12502937biostudies-literatureAge-Related Changes and Spinal Sagittal Alignment in Asymptomatic Community Dwelling Adults Over 50.PMC12502937Li XPan FWang DLu SWang WLiu CKong CZhu WChen XWang ZfalseAge-Related Changes and Spinal Sagittal Alignment in Asymptomatic Community Dwelling Adults Over 50.<h4>Study design</h4>Monocentric, retrospective, cross-sectional study.<h4>Objective</h4>To investigate the age-related normative values of sagittal parameters and establish their relationships in asymptomatic community-dwelling adults aged over 50.<h4>Background context</h4>Degenerative changes in the spine with aging alter the sagittal balance, causing spine pathologies. However, there was a lack of comprehensive study on age-related normative values of sagittal alignment and their relationship during degenerative evolution.<h4>Methods</h4>Among a total of 1,370 volunteers, 701 asymptomatic volunteers were recruited. Participants underwent a lateral X-ray, and sagittal parameters were assessed using a customized computer application.<h4>Results</h4>Age showed a stronger correlation with 2025-01-01T00:00:00Z2025 Feb2026-06-04T06:53:29.318Z2026-05-06T03:13:31.747ZS-EPMC125029373993178710.1097/BRS.0000000000005248