{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Stein JS"],"funding":["NIDA NIH HHS","National Institute on Drug Abuse"],"pagination":["e70056"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12503084"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["124(3)"],"pubmed_abstract":["Using the Experimental Tobacco Marketplace, we examined the effects of e-liquid freebase nicotine strength (3-24 mg/mL) and e-liquid price (US$0.25-$1.00/mL) on behavioral economic substitution for cigarettes in dual cigarette/e-cigarette (n = 41) and exclusive cigarette (n = 40) users. Subjective effects of nicotine strength were also examined. All nicotine strengths served as a substitute for combustible cigarettes, with greater substitution observed in dual users. When analyzing e-liquid volume purchased (mL), nicotine strength did not influence substitution; however, when analyzing e-liquid nicotine purchased (mg), degree of substitution increased as a function of nicotine strength. Additionally, higher nicotine strengths reduced the volume and probability of e-liquid purchasing, incre"],"journal":["Journal of the experimental analysis of behavior"],"pubmed_title":["Does e-cigarette nicotine strength influence substitution for combustible cigarettes?"],"pmcid":["PMC12503084"],"funding_grant_id":["R21 DA046339","5R21DA046339"],"pubmed_authors":["Brown JM","Stein JS","Curran KM","Tegge AN","Bickel WK"],"additional_accession":[]},"is_claimable":false,"name":"Does e-cigarette nicotine strength influence substitution for combustible cigarettes?","description":"Using the Experimental Tobacco Marketplace, we examined the effects of e-liquid freebase nicotine strength (3-24 mg/mL) and e-liquid price (US$0.25-$1.00/mL) on behavioral economic substitution for cigarettes in dual cigarette/e-cigarette (n = 41) and exclusive cigarette (n = 40) users. Subjective effects of nicotine strength were also examined. All nicotine strengths served as a substitute for combustible cigarettes, with greater substitution observed in dual users. When analyzing e-liquid volume purchased (mL), nicotine strength did not influence substitution; however, when analyzing e-liquid nicotine purchased (mg), degree of substitution increased as a function of nicotine strength. Additionally, higher nicotine strengths reduced the volume and probability of e-liquid purchasing, incre","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Nov","modification":"2026-07-15T07:34:02.989Z","creation":"2026-07-02T03:08:41.275Z"},"accession":"S-EPMC12503084","cross_references":{"pubmed":["41055893"],"doi":["10.1002/jeab.70056"]}}