{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["16"],"submitter":["Ruiz SE"],"pubmed_abstract":["Antimicrobial resistance (AMR) is a critical global challenge, yet the role of environmental dissemination of antibiotic-resistant bacteria remains underexplored, particularly in developing regions. This study investigated urban wastewater overflows from public streets as vectors for extended-spectrum-β-lactamase (ESBL)- and carbapenemase-producing <i>Enterobacterales</i> and <i>Aeromonas</i> in the Suquía River (Córdoba, Argentina). Sixty-two water samples were analyzed for coliform counts, antimicrobial susceptibility, and resistance genes. Horizontal gene transfer was assessed by conjugation. Sixty-five ESBL- and/or carbapenemase-producing isolates were recovered, including six carbapenemase producers subjected to whole-genome sequencing (WGS). Urban wastewater exhibited coliform levels"],"journal":["Frontiers in microbiology"],"pagination":["1669531"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12504239"],"repository":["biostudies-literature"],"pubmed_title":["Urban wastewater overflows as hotspots for dissemination of bacteria producing extended-spectrum β-lactamases and carbapenemases in the Suquia River, Argentina."],"pmcid":["PMC12504239"],"pubmed_authors":["Sola C","Panzetta ME","Ame V","Saka HA","Toselli R","Der Ohannesian M","Amieva C","Rollan MDR","Giraudo FJ","Ruiz SE","Morandini FN","Irrazabal MG","Lipari FG","Valdes ME"],"additional_accession":[]},"is_claimable":false,"name":"Urban wastewater overflows as hotspots for dissemination of bacteria producing extended-spectrum β-lactamases and carbapenemases in the Suquia River, Argentina.","description":"Antimicrobial resistance (AMR) is a critical global challenge, yet the role of environmental dissemination of antibiotic-resistant bacteria remains underexplored, particularly in developing regions. This study investigated urban wastewater overflows from public streets as vectors for extended-spectrum-β-lactamase (ESBL)- and carbapenemase-producing <i>Enterobacterales</i> and <i>Aeromonas</i> in the Suquía River (Córdoba, Argentina). Sixty-two water samples were analyzed for coliform counts, antimicrobial susceptibility, and resistance genes. Horizontal gene transfer was assessed by conjugation. Sixty-five ESBL- and/or carbapenemase-producing isolates were recovered, including six carbapenemase producers subjected to whole-genome sequencing (WGS). Urban wastewater exhibited coliform levels","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025","modification":"2026-06-04T10:03:31.112Z","creation":"2026-06-02T03:07:43.529Z"},"accession":"S-EPMC12504239","cross_references":{"pubmed":["41070122"],"doi":["10.3389/fmicb.2025.1669531"]}}