{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["15(44)"],"submitter":["Tan F"],"pubmed_abstract":["Butralin is a selective pre-budding agent. It is relatively immobile in the substrate after application, and its transmission through the food chain poses a potential threat to human health. In this study, we isolated a butralin-degrading strain FC02, and identified it as <i>Bacillus velezensis</i>. Optimization of butralin degradation with Box-Behnken design resulted in 89.12% degradation at pH 8.4, OD<sub>600</sub> = 2.5, 35.0 °C, and 200 mg FC02. Strain FC02 efficiently converted butralin into five products through nitro-reduction, dealkylation, and hydroxylation reactions, differing from the mechanisms and pathways in other strains. Genomics and transcriptomic analyses revealed that nitroreductase genes are involved in the nitro-reduction process of butralin degradation. Here, we explo"],"journal":["RSC advances"],"pagination":["37461-37473"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12506887"],"repository":["biostudies-literature"],"pubmed_title":["Biodegradation mechanism of butralin by a newly isolated &lt;i&gt;Bacillus velezensis&lt;/i&gt; FC02."],"pmcid":["PMC12506887"],"pubmed_authors":["Cao H","Zong H","Ling W","Xu C","Tan F","Yu J","Feng C","Chen D"],"additional_accession":[]},"is_claimable":false,"name":"Biodegradation mechanism of butralin by a newly isolated &lt;i&gt;Bacillus velezensis&lt;/i&gt; FC02.","description":"Butralin is a selective pre-budding agent. It is relatively immobile in the substrate after application, and its transmission through the food chain poses a potential threat to human health. In this study, we isolated a butralin-degrading strain FC02, and identified it as <i>Bacillus velezensis</i>. Optimization of butralin degradation with Box-Behnken design resulted in 89.12% degradation at pH 8.4, OD<sub>600</sub> = 2.5, 35.0 °C, and 200 mg FC02. Strain FC02 efficiently converted butralin into five products through nitro-reduction, dealkylation, and hydroxylation reactions, differing from the mechanisms and pathways in other strains. Genomics and transcriptomic analyses revealed that nitroreductase genes are involved in the nitro-reduction process of butralin degradation. Here, we explo","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Oct","modification":"2026-06-05T07:51:04.965Z","creation":"2026-05-14T03:12:29.7Z"},"accession":"S-EPMC12506887","cross_references":{"pubmed":["41069376"],"doi":["10.1039/d5ra02138c"]}}