{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["15(1)"],"submitter":["Abozaid D"],"pubmed_abstract":["Dental composites are widely used restorative materials but secondary caries to the restored tooth, polymerization shrinkage, and mechanical failure, limiting their longevity. Incorporating nanoparticles synthesized via eco-friendly methods offers a promising strategy to enhance composite performance. This study introduces a novel, eco-friendly strategy to enhance dental composite resins by incorporating TiO₂-NPs synthesized using Vitis vinifera extract. This study uniquely employs Vitis vinifera, rich in flavonoids and phenolics, as a reducing and capping agent, and for the first time integrates molecular docking analysis to explore the mechanistic antimicrobial interaction between TiO₂-NPs and Streptococcus mutans glucosyltransferase. The research evaluates the impact of these green-synt"],"journal":["Scientific reports"],"pagination":["35042"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12508154"],"repository":["biostudies-literature"],"pubmed_title":["Antimicrobial mechanical and molecular docking analysis of dental composite resin incorporating green synthesized titanium dioxide nanoparticles from Vitis vinifera extract."],"pmcid":["PMC12508154"],"pubmed_authors":["El-Aal MA","Abdelmonem M","Saleh AM","Azab A","Ibrahim MA","Eldin ZE","Abozaid D"],"additional_accession":[]},"is_claimable":false,"name":"Antimicrobial mechanical and molecular docking analysis of dental composite resin incorporating green synthesized titanium dioxide nanoparticles from Vitis vinifera extract.","description":"Dental composites are widely used restorative materials but secondary caries to the restored tooth, polymerization shrinkage, and mechanical failure, limiting their longevity. Incorporating nanoparticles synthesized via eco-friendly methods offers a promising strategy to enhance composite performance. This study introduces a novel, eco-friendly strategy to enhance dental composite resins by incorporating TiO₂-NPs synthesized using Vitis vinifera extract. This study uniquely employs Vitis vinifera, rich in flavonoids and phenolics, as a reducing and capping agent, and for the first time integrates molecular docking analysis to explore the mechanistic antimicrobial interaction between TiO₂-NPs and Streptococcus mutans glucosyltransferase. The research evaluates the impact of these green-synt","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Oct","modification":"2026-06-04T07:42:50.274Z","creation":"2026-05-06T03:12:58.877Z"},"accession":"S-EPMC12508154","cross_references":{"pubmed":["41062669"],"doi":["10.1038/s41598-025-20989-5"]}}