{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Yang Y"],"funding":["Shandong provincial Natural Science Foundation, China"],"pagination":["416"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12509345"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["25(1)"],"pubmed_abstract":["<h4>Objective</h4>The triglyceride-glucose (TyG) index and its related parameters are biomarkers of insulin resistance (IR) and maybe of great significance for predicting the occurrence of stroke. This systematic review and meta-analysis aimed to summarize the relationship between TyG and its related parameters with the risks of stroke.<h4>Methods</h4>By searching the Cochrane Library, Embase, and PubMed databases, we obtained prospective cohort studies that reported the hazard ratios (HRs) and their 95% confidence intervals (CIs) for the association between the TyG index and its related parameters (TyG-BMI, TyG-WC, TyG-WHtR) and stroke incidence. The results were combined using a random-effects model.<h4>Results</h4>This meta-analysis included 21 prospective cohort studies with a total of"],"journal":["BMC neurology"],"pubmed_title":["Association of triglyceride-glucose index and its related parameters with the risk of stroke: a meta-analysis."],"pmcid":["PMC12509345"],"funding_grant_id":["No. ZR2021MH180"],"pubmed_authors":["Sun L","Yang Y","Bai R","Meng M","Li B","Cheng Y","Wang L"],"additional_accession":[]},"is_claimable":false,"name":"Association of triglyceride-glucose index and its related parameters with the risk of stroke: a meta-analysis.","description":"<h4>Objective</h4>The triglyceride-glucose (TyG) index and its related parameters are biomarkers of insulin resistance (IR) and maybe of great significance for predicting the occurrence of stroke. This systematic review and meta-analysis aimed to summarize the relationship between TyG and its related parameters with the risks of stroke.<h4>Methods</h4>By searching the Cochrane Library, Embase, and PubMed databases, we obtained prospective cohort studies that reported the hazard ratios (HRs) and their 95% confidence intervals (CIs) for the association between the TyG index and its related parameters (TyG-BMI, TyG-WC, TyG-WHtR) and stroke incidence. The results were combined using a random-effects model.<h4>Results</h4>This meta-analysis included 21 prospective cohort studies with a total of","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Oct","modification":"2026-06-04T08:44:10.246Z","creation":"2026-05-07T03:09:20.964Z"},"accession":"S-EPMC12509345","cross_references":{"pubmed":["41068686"],"doi":["10.1186/s12883-025-04349-4"]}}