biostudies-literatureUnknown89DAMASCUS CollaborativeBowel Research UK<h4>Background</h4>Acute diverticulitis is a common condition that can be a surgical emergency. Its prevalence is increasing worldwide, however optimal management remains unclear. This study aimed to determine current practice and short-term outcomes globally.<h4>Methods</h4>A prospective, international cohort study of patients presenting with acute diverticulitis to secondary care units was undertaken. Countries were stratified by geographical region and income groups. Patients presenting over a 44-week recruitment period (1/10/2020-31/8/2021) were included. Patient and disease covariates, management and short-term outcomes were captured in a secure web application. The primary outcome of interest was the geographical variation in presentation and treatment. The secondary outcome was treaEClinicalMedicine103548https://www.ebi.ac.uk/biostudies/studies/S-EPMC12512976biostudies-literatureGlobal hospital-based disease management of acute diverticulitis: a prospective, international cohort study.PMC12512976Johnson MPAngus LFelice BAngus MJanahan SMuzan AMiguel JLR MMSanjeev PFioralba PNicola CLucy YMaitham AMustafa KNatalie SIrmgard E KJan GSalih SDale VMarwaIsa BJan KAles KJNicola PNicola RGiuseppina VTee LSJan SRin PSChristof MPantelis VClaudia SFrancisco Javier EFAbdulwahid AWRachel HFatma KEmilio PRParas BUgo GClaudia BAly KAAmir GAndrew JAngela WFrancisco MSAngela RJaroslav PAndrew MGakul BPhilipp SAdeline RFarhat AAlperen BYAngela BYasser AALuke TSameh BYGiles BSAntonio GCHussam NMichael Pak-Kai WLuke DZafer UNGiovanni TJose PTayfun YSoha YElisabetta TAdam MAnas AAnas BAlmu'atasim KEray TAPanagiotis KMahul PMumtaz BEmily KEmily LEmily MClare BAnas SClare AFrancisco Javier JMRajeev PPanna PChristina DPablo COAlexander FTElif CElif BOlga 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DOlatoyosi WChristopher PMohd Nizam MHGiuseppe TJulia CChristopher LGiuseppe SIsacco MWejdan IGiuseppe LCarlos Javier GDCharles LManuel OVUmesh JGiuseppe BGiuseppe CAndreas LYasmine AMHazim AArmin FNagm Eldin AEAbdurrahman ATarek ETClara GFOssaid QChetan PFrancesca MEdoardo VPaulo CFrancesca SAdrian YSadhasivam RJamie MCarlotta BMohaemedraed ESimon EMarin-Blazquez Antonio AReetta HSezai LAhmad QStephen OMichael REgidio MMichael SMaria CPSimon LAhmad UPaulina MVMichael WAmr HHerald NArturo RMichael LMassimiliano CJames HSMichael CMichael FMichael GMichael HCarlos RSmart NJZulfu BDomenico GCarlos JEfstratios KNoor ALDeepika BJulian CDonato F AMina Ragaa Fekry AIrene KJack BSabrina GFederico MCarmelo CEithar AEnrique CRFederico GIyad IFarshid ENicoletta Sveva PFMichal WMohamed FAAnna LAnna MRio Paolo DKemal AAdil RStephanie OMerve TIkhtiyar AAnna BAndrey KMohammed A BRecayi CHeba NHamdy AEAthanasios KHidde KJim BImran RAurelie VBenjamin WAfnan MAnna PJim KNicolas ABenjamin SAbigail HOmar MNicolas LAbigail COmar KAmira AAOmar LMandeep KAlex HAlex CBenjamin CCharlotte PRodrigo VSDAlex WGiorgio LfalseGlobal hospital-based disease management of acute diverticulitis: a prospective, international cohort study.<h4>Background</h4>Acute diverticulitis is a common condition that can be a surgical emergency. Its prevalence is increasing worldwide, however optimal management remains unclear. This study aimed to determine current practice and short-term outcomes globally.<h4>Methods</h4>A prospective, international cohort study of patients presenting with acute diverticulitis to secondary care units was undertaken. Countries were stratified by geographical region and income groups. Patients presenting over a 44-week recruitment period (1/10/2020-31/8/2021) were included. Patient and disease covariates, management and short-term outcomes were captured in a secure web application. The primary outcome of interest was the geographical variation in presentation and treatment. The secondary outcome was trea2025-01-01T00:00:00Z2025 Nov2026-06-06T11:26:40.521Z2026-05-29T03:13:02.936ZS-EPMC125129764107902810.1016/j.eclinm.2025.103548