{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Li X"],"funding":["Beijing Anorectal Hospital","Beijing Anorectal Hospital (Beijing Erlong Lu Hospital)"],"pagination":["481"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12522433"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["25(1)"],"pubmed_abstract":["Background
Fournier's gangrene (FG) is a life-threatening infection associated with high mortality and often necessitates urgent surgical intervention. Vacuum sealing drainage (VSD) has emerged as a promising adjunct to surgical debridement; however, its impact on antibiotic stewardship remains inadequately studied. This study compares the efficacy of VSD and conventional dressings in the management of FG.Methods
In this single-center retrospective study, 104 patients with Fournier's gangrene (FG) treated between January 2022 and December 2023 were analyzed. Patients were categorized into VSD (n = 42) and conventional dressing (n = 62) groups following surgical debridement. Data included demographics, comorbidities, infection sites, Laboratory Risk Indicator for Necrotizing"],"journal":["BMC surgery"],"pubmed_title":["Comparison between vacuum sealing drainage (VSD) and conventional dressing for fournier's gangrene: a single-centre retrospective study."],"pmcid":["PMC12522433"],"funding_grant_id":["2024ELLHA-011-01"],"pubmed_authors":["Li X","Niu S","Li J","Wang Q","Liu L","Zhang Z","Zhang Y","Cao D","Xiong F","Qi S","Mu S","Liu W"],"additional_accession":[]},"is_claimable":false,"name":"Comparison between vacuum sealing drainage (VSD) and conventional dressing for fournier's gangrene: a single-centre retrospective study.","description":"Background
Fournier's gangrene (FG) is a life-threatening infection associated with high mortality and often necessitates urgent surgical intervention. Vacuum sealing drainage (VSD) has emerged as a promising adjunct to surgical debridement; however, its impact on antibiotic stewardship remains inadequately studied. This study compares the efficacy of VSD and conventional dressings in the management of FG.Methods
In this single-center retrospective study, 104 patients with Fournier's gangrene (FG) treated between January 2022 and December 2023 were analyzed. Patients were categorized into VSD (n = 42) and conventional dressing (n = 62) groups following surgical debridement. Data included demographics, comorbidities, infection sites, Laboratory Risk Indicator for Necrotizing","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Oct","modification":"2026-06-04T12:01:49.145Z","creation":"2026-05-09T03:07:42.961Z"},"accession":"S-EPMC12522433","cross_references":{"pubmed":["41094492"],"doi":["10.1186/s12893-025-03242-8"]}}