{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Yang S"],"funding":["Shaanxi Provincial Science and Technology Department","Shaanxi Provincial Administration of Traditional Chinese Medicine","Shaanxi Provincial Department of Education Scientific Research Programme Project","The Subject Innovation Team of Quality Control and Resources Development of \"Qin Medicine\" of Shaanxi University of Chinese Medicine"],"pagination":["1375"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12523036"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["25(1)"],"pubmed_abstract":["Sclerified endocarp formation represents a defining developmental feature in Cornus officinalis drupes. We systematically investigated cytological dynamics and lignin metabolism to define the mechanistic basis of endocarp sclerification during Cornus officinalis fruit development. Results demonstrated that endocarp sclerification coincided with a significant increase in lignin content. Stone cell density exhibited developmental variation (239-529 piece·mg-1; mean: 400 piece·mg-1), while the microscopic characteristic index of stone cells progressively increased and stabilized at fruit maturity. Critically, the activities of pivotal lignin biosynthesis enzymes (PAL, CCR, CAD, POD) peaked during early fruit development and subsequently declined with progressive lignin accumulation-a trend co"],"journal":["BMC plant biology"],"pubmed_title":["Lignin: the primary component responsible for endocarp sclerosis in the development of Cornus officinalis fruit."],"pmcid":["PMC12523036"],"funding_grant_id":["NO.22JC028","2025JC-YBMS-1055","L2024-QCY-ZYYJJQ-X74","23JP037","2019-QN01"],"pubmed_authors":["Zhang G","Li Y","Zhang X","Qin Y","Gao J","Zhang M","Chen Y","Peng L","Yang S"],"additional_accession":[]},"is_claimable":false,"name":"Lignin: the primary component responsible for endocarp sclerosis in the development of Cornus officinalis fruit.","description":"Sclerified endocarp formation represents a defining developmental feature in Cornus officinalis drupes. We systematically investigated cytological dynamics and lignin metabolism to define the mechanistic basis of endocarp sclerification during Cornus officinalis fruit development. Results demonstrated that endocarp sclerification coincided with a significant increase in lignin content. Stone cell density exhibited developmental variation (239-529 piece·mg-1; mean: 400 piece·mg-1), while the microscopic characteristic index of stone cells progressively increased and stabilized at fruit maturity. Critically, the activities of pivotal lignin biosynthesis enzymes (PAL, CCR, CAD, POD) peaked during early fruit development and subsequently declined with progressive lignin accumulation-a trend co","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Oct","modification":"2026-06-04T11:50:36.321Z","creation":"2026-05-08T03:11:08.715Z"},"accession":"S-EPMC12523036","cross_references":{"pubmed":["41087894"],"doi":["10.1186/s12870-025-07347-3"]}}