{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["14(17)"],"submitter":["Kubo S"],"pubmed_abstract":["<h4>Background</h4>The association of outcomes with initial clip selection has not been investigated in patients undergoing transcatheter edge-to-edge repair with the MitraClip G4.<h4>Methods</h4>We analyzed 2257 patients receiving the MitraClip G4 according to the initial clip type: short (NT/NTW) versus long (XT/XTW) and narrow (NT/XT) versus wide (NTW/XTW). We performed a propensity-matched analysis of baseline anatomical features in patients with primary and secondary mitral regurgitation (MR).<h4>Results</h4>The proportions of the initial clip types were as follows: NT, 18.9%; NTW, 41.7%; XT, 5.1%; and XTW, 34.3%. The proportions of the MR severity ≤1+ at discharge and 1 year were not significantly different among the 4 clip types. The incidence of death or heart failure hospitalizati"],"journal":["Journal of the American Heart Association"],"pagination":["e041907"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12553428"],"repository":["biostudies-literature"],"pubmed_title":["Real-World Outcomes of the Initial Clip Selection for Transcatheter Edge-to-Edge Repair Using the MitraClip G4 From the Optimized Catheter Valvular Intervention-Mitral Registry."],"pmcid":["PMC12553428"],"pubmed_authors":["Miyahara K","Otsuki H","Saito T","Miyahara D","Maruyama M","Saito M","Kawamura T","Nishio H","Ono S","Ohara H","Irie Y","Kurashima S","Tsuru Y","Otsuka T","Hosoda N","Doi T","Doi S","Yamada N","Yamada M","Yoshikawa M","Saji M","Tsunamoto H","Shitan H","Ohara M","Okabe K","Kuroda M","Onuki K","Sobajima M","Tazawa D","Naganuma T","Sasaki K","Shishido K","Osakada K","Yanagisawa J","Natsumeda M","Tsuruta H","Yamasaki K","Koga M","Sato Y","Hioki H","Koyanagi C","Horita R","Okamatsu H","Kanno H","Izumi Y","Kobari Y","Inagaki Y","Ushijima R","Sato D","Harano Y","Torii S","Honda K","Hada T","Tsunaki T","Ryuzaki T","Inagaki M","Nakano K","Miyamoto J","Imamura T","Kaneko T","Yamabe T","Nishio R","Shinada K","Fukunaga M","Koyama Y","Ko E","Miyasaka M","Takagi K","Suenaga T","Otake R","Otani A","Shirai S","Tsuchida Y","Horibata Y","Yasuda M","Ueno H","Sugiyama Y","Maeda M","Nakamura N","Ueno Y","Hayashida K","Abe R","Kurita A","Onoda H","Nakamura T","Katagiri Y","Hida Y","Sakata S","Aihara K","Onishi K","Ijichi T","Satomi N","Nishiura N","Omiya J","Horinouchi H","Horio E","Nagai T","Tokuda T","Teng Y","Murakami T","Amaki M","Murakami Y","Suzuyama H","Watanabe Y","Izumo M","Ishizu K","Okazaki S","Iwata J","Nemoto Y","Okubo M","Shibahashi E","Fukushige S","Miyazaki S","Moriyama N","Miyazaki M","Okubo Y","Nonaka H","Tabata M","Hiruma T","Sakakura T","Tabata H","Terauchi K","Imai S","Ochiai T","Kitai T","Moriizumi T","Kogure T","Koike H","Yamanaka F","Higuma T","Kamioka N","Kajino A","Kagase A","Miura M","Katayama T","Hachinohe D","Shibata K","Kubo S","Tanaka S","Yoshida A","Isotani A","Iseki Y","Imaeda S","Tanaka K","Cerebral N","Tanaka J","Gonda Y","Tanaka M","Katsumata Y","Kaihara T","Shimura T","Saigan M","Fujita M","Okamoto M","Kono H","Yoshida T","Kai T","Okuno T","Arita R","Fujita K","Sone K","OCEAN‐Mitral investigators","Kondo Y","Arai M","Fukuda N","Konami Y","Kobayashi T","Togashi D","Kuze Y","Goto S","Kobayashi K","Ohno Y","Nishimura Y","Nishikawa J","Kito K","Yamamoto K","Nakashima M","Yamamoto M","Asami M","Tada N","Hasegawa S","Nakazawa G","Nakashima K","Sago M","Sakai K","Enta Y","Munehisa Y","Soejima N","Bota H","Miyashita H","Noda S","Nakashima Y","Mushiake K","Kodama K","Yamawaki M","Sakamoto T","Yuki H","Ouchi T","Kawahata R","Morofuji T","Shimizu K","Maruo T","Takahashi T","Kato J","Yamaguchi R","Mizuno S","Takahashi N","Yamaguchi J","Tani T","Murata R","Kagiyama N","Matsumoto S","Higuchi R","Matsumoto T","Miyoshi T","Maekawara S","Okada A","Higami H","Horiuchi Y","Miyawaki N","Kobayashi Y","Shirakawa K","Arakawa M","Kuwata S","Nakagawa S","Kawamoto T"],"additional_accession":[]},"is_claimable":false,"name":"Real-World Outcomes of the Initial Clip Selection for Transcatheter Edge-to-Edge Repair Using the MitraClip G4 From the Optimized Catheter Valvular Intervention-Mitral Registry.","description":"<h4>Background</h4>The association of outcomes with initial clip selection has not been investigated in patients undergoing transcatheter edge-to-edge repair with the MitraClip G4.<h4>Methods</h4>We analyzed 2257 patients receiving the MitraClip G4 according to the initial clip type: short (NT/NTW) versus long (XT/XTW) and narrow (NT/XT) versus wide (NTW/XTW). We performed a propensity-matched analysis of baseline anatomical features in patients with primary and secondary mitral regurgitation (MR).<h4>Results</h4>The proportions of the initial clip types were as follows: NT, 18.9%; NTW, 41.7%; XT, 5.1%; and XTW, 34.3%. The proportions of the MR severity ≤1+ at discharge and 1 year were not significantly different among the 4 clip types. The incidence of death or heart failure hospitalizati","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-06-05T04:55:14.592Z","creation":"2026-05-13T14:28:50.257Z"},"accession":"S-EPMC12553428","cross_references":{"pubmed":["40879026"],"doi":["10.1161/JAHA.125.041907"]}}