{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["14(17)"],"submitter":["Karimzad K"],"pubmed_abstract":["<h4>Background</h4>Radiation therapy (RT) can cause cardiac implantable electronic device (CIED) malfunction, primarily reset. Given changes in RT and CIED technologies, large observational studies examining malfunction of contemporary CIEDs during modern-day RT are needed to guide clinical practice.<h4>Methods</h4>Electronic medical records of all consecutive patients with CIEDs who underwent RT at a large tertiary cancer center between January 2015 and January 2022 were reviewed. All patients had CIED interrogation before and after completion of RT. Device-related data and RT-specific variables were collected. Statistical analyses were performed at the RT course level.<h4>Results</h4>Over a period of 7 years, 677 patients (median age, 74 [interquartile range, 67. 8-79.2] years; 72% men) "],"journal":["Journal of the American Heart Association"],"pagination":["e042937"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12553441"],"repository":["biostudies-literature"],"pubmed_title":["Safety of Contemporary Radiation Therapy in Patients With Cardiac Implantable Electronic Devices: Implications for Clinical Practice."],"pmcid":["PMC12553441"],"pubmed_authors":["Chauhan S","Wagner D","Peeler C","Karimzad K","Iliescu C","Shah S","Tsai J","Chacon Portillo M","Deswal A","Strang A","Amatullah A","Song J","Vachhani S","Dougherty AH","Thakar D","Pollard-Larkin J","Kry SF","Miller C","Mir Zaman Shah K","Koduri A","Lopez D","Durand JB","Kantharia B"],"additional_accession":[]},"is_claimable":false,"name":"Safety of Contemporary Radiation Therapy in Patients With Cardiac Implantable Electronic Devices: Implications for Clinical Practice.","description":"<h4>Background</h4>Radiation therapy (RT) can cause cardiac implantable electronic device (CIED) malfunction, primarily reset. Given changes in RT and CIED technologies, large observational studies examining malfunction of contemporary CIEDs during modern-day RT are needed to guide clinical practice.<h4>Methods</h4>Electronic medical records of all consecutive patients with CIEDs who underwent RT at a large tertiary cancer center between January 2015 and January 2022 were reviewed. All patients had CIED interrogation before and after completion of RT. Device-related data and RT-specific variables were collected. Statistical analyses were performed at the RT course level.<h4>Results</h4>Over a period of 7 years, 677 patients (median age, 74 [interquartile range, 67. 8-79.2] years; 72% men) ","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-06-05T04:54:41.633Z","creation":"2026-05-13T14:28:46.517Z"},"accession":"S-EPMC12553441","cross_references":{"pubmed":["40847479"],"doi":["10.1161/JAHA.125.042937"]}}