biostudies-literatureUnknown5(5)Onder R<h4>Aims</h4>Older patients with AF (≥65 years) have on average four additional comorbidities. Comorbidity management requires a systematic approach for identification, and interdisciplinary care, often lacking in clinical practice. The EHRA-PATHS project's overall aim is to create an approach to systematically address multimorbidity in older patients with AF.<h4>Methods and results</h4>This project involves a consortium of 14 partners from 11 European countries. The comorbidity care pathways were developed using a stepwise approach. (i) A literature study. (ii) Online meetings/discussions to create structured care pathways. (iii) A two-round Delphi study for consensus on the final pathways (agreement ≥80%) and to rank the comorbidities for priority. (iv) Selection of comorbidities for evaEuropean heart journal openoeaf120https://www.ebi.ac.uk/biostudies/studies/S-EPMC12555002biostudies-literatureDevelopment of three-step holistic care pathways to detect and manage comorbidities in patients with atrial fibrillation: the Horizon 2020 EHRA-PATHS consortium.PMC12555002Hofer DFarkowski MMLopez TPotpara TRienstra MLee GMerino JLOnder RLobeek Mde Oliveira Figueiredo MJLinz DCollins RSanders PSterlinski MHeidbuchel HLau CPSvennberg EVijgen JMcAuliffe CShamloo ASDabrowski RHereijgers MJMDesteghe Lvan Deutekom CVan Gelder IfalseDevelopment of three-step holistic care pathways to detect and manage comorbidities in patients with atrial fibrillation: the Horizon 2020 EHRA-PATHS consortium.<h4>Aims</h4>Older patients with AF (≥65 years) have on average four additional comorbidities. Comorbidity management requires a systematic approach for identification, and interdisciplinary care, often lacking in clinical practice. The EHRA-PATHS project's overall aim is to create an approach to systematically address multimorbidity in older patients with AF.<h4>Methods and results</h4>This project involves a consortium of 14 partners from 11 European countries. The comorbidity care pathways were developed using a stepwise approach. (i) A literature study. (ii) Online meetings/discussions to create structured care pathways. (iii) A two-round Delphi study for consensus on the final pathways (agreement ≥80%) and to rank the comorbidities for priority. (iv) Selection of comorbidities for eva2025-01-01T00:00:00Z2025 Sep2026-07-15T14:34:58.604Z2026-07-06T03:08:56.625ZS-EPMC125550024117175210.1093/ehjopen/oeaf120