{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Husain SA"],"funding":["NIDDK NIH HHS","NIMHD NIH HHS","Hennepin Healthcare Research Institute"],"pagination":["e70167"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12558682"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["29(7)"],"pubmed_abstract":["<h4>Background</h4>Changes to the calculation of the Kidney Donor Profile Index (KDPI) have lowered the KDPI of hepatitis C (HCV+) donor kidneys; therefore, increasing the proportion of pediatric-prioritized kidneys that are HCV+. We aimed to study consent rates for HCV+ kidneys among pediatric kidney transplant candidates.<h4>Methods</h4>We identified pediatric candidates waitlisted from 2019 to 2024 and excluded those who received a living donor transplant. We used logistic regression to identify candidate characteristics associated with HCV+ offer consent and Cox proportional hazards models to determine the association between HCV+ offer consent and the rate of deceased donor transplantation.<h4>Results</h4>Among 3202 candidates included in the analysis, 124 (4%) consented to receive HC"],"journal":["Pediatric transplantation"],"pubmed_title":["Consent to Receive Offers for Kidneys From Donors With Hepatitis C Among Pediatric Kidney Transplant Candidates in the United States."],"pmcid":["PMC12558682"],"funding_grant_id":["R01 DK114893","K23DK133729","R01 DK126739","K23 DK133729","R01 DK120886","R01 MD014161","U01 DK130058","U01 DK116066"],"pubmed_authors":["Potluri V","Yu M","Maclay LM","Amaral S","Mohan S","Husain SA","McAteer J","Schold JD"],"additional_accession":[]},"is_claimable":false,"name":"Consent to Receive Offers for Kidneys From Donors With Hepatitis C Among Pediatric Kidney Transplant Candidates in the United States.","description":"<h4>Background</h4>Changes to the calculation of the Kidney Donor Profile Index (KDPI) have lowered the KDPI of hepatitis C (HCV+) donor kidneys; therefore, increasing the proportion of pediatric-prioritized kidneys that are HCV+. We aimed to study consent rates for HCV+ kidneys among pediatric kidney transplant candidates.<h4>Methods</h4>We identified pediatric candidates waitlisted from 2019 to 2024 and excluded those who received a living donor transplant. We used logistic regression to identify candidate characteristics associated with HCV+ offer consent and Cox proportional hazards models to determine the association between HCV+ offer consent and the rate of deceased donor transplantation.<h4>Results</h4>Among 3202 candidates included in the analysis, 124 (4%) consented to receive HC","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Nov","modification":"2026-06-05T07:12:38.966Z","creation":"2026-05-14T03:08:56.406Z"},"accession":"S-EPMC12558682","cross_references":{"pubmed":["40931645"],"doi":["10.1111/petr.70167"]}}