biostudies-literatureHusain SANIDDK NIH HHSNIMHD NIH HHSHennepin Healthcare Research Institutee70167https://www.ebi.ac.uk/biostudies/studies/S-EPMC12558682biostudies-literatureUnknown29(7)<h4>Background</h4>Changes to the calculation of the Kidney Donor Profile Index (KDPI) have lowered the KDPI of hepatitis C (HCV+) donor kidneys; therefore, increasing the proportion of pediatric-prioritized kidneys that are HCV+. We aimed to study consent rates for HCV+ kidneys among pediatric kidney transplant candidates.<h4>Methods</h4>We identified pediatric candidates waitlisted from 2019 to 2024 and excluded those who received a living donor transplant. We used logistic regression to identify candidate characteristics associated with HCV+ offer consent and Cox proportional hazards models to determine the association between HCV+ offer consent and the rate of deceased donor transplantation.<h4>Results</h4>Among 3202 candidates included in the analysis, 124 (4%) consented to receive HCPediatric transplantationConsent to Receive Offers for Kidneys From Donors With Hepatitis C Among Pediatric Kidney Transplant Candidates in the United States.PMC12558682R01 DK114893K23DK133729R01 DK126739K23 DK133729R01 DK120886R01 MD014161U01 DK130058U01 DK116066Potluri VYu MMaclay LMAmaral SMohan SHusain SAMcAteer JSchold JDfalseConsent to Receive Offers for Kidneys From Donors With Hepatitis C Among Pediatric Kidney Transplant Candidates in the United States.<h4>Background</h4>Changes to the calculation of the Kidney Donor Profile Index (KDPI) have lowered the KDPI of hepatitis C (HCV+) donor kidneys; therefore, increasing the proportion of pediatric-prioritized kidneys that are HCV+. We aimed to study consent rates for HCV+ kidneys among pediatric kidney transplant candidates.<h4>Methods</h4>We identified pediatric candidates waitlisted from 2019 to 2024 and excluded those who received a living donor transplant. We used logistic regression to identify candidate characteristics associated with HCV+ offer consent and Cox proportional hazards models to determine the association between HCV+ offer consent and the rate of deceased donor transplantation.<h4>Results</h4>Among 3202 candidates included in the analysis, 124 (4%) consented to receive HC2025-01-01T00:00:00Z2025 Nov2026-06-05T07:12:38.966Z2026-05-14T03:08:56.406ZS-EPMC125586824093164510.1111/petr.70167