{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12"],"submitter":["Di Minno A"],"pubmed_abstract":["<h4>Introduction</h4>Impaired fasting glycemia (IFG) puts carriers at a significantly higher risk of developing type 2 diabetes and cardiovascular disease. Lifestyle changes, such as increased physical activity and a healthy diet rich in fiber and low in sugar, can often reverse prediabetes and significantly reduce the risk of progressing to type 2 diabetes metabolic disorders, especially diabetes (1).<h4>Methods</h4>This randomized clinical trial aims to evaluate the efficacy and tolerability of a food supplement (FS) containing <i>Citrus limon</i> L. Osbeck and <i>Vitis vinifera</i> L. extracts, hesperidin from <i>Citrus sinensis</i> L. Osbeck, and chromium, in individuals with impaired fasting blood glucose , with the final goal of investigating whether the use of a combination of ingre"],"journal":["Frontiers in nutrition"],"pagination":["1671102"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12558782"],"repository":["biostudies-literature"],"pubmed_title":["Impact of a food supplement containing &lt;i&gt;Citrus limon&lt;/i&gt; L. Osbeck and &lt;i&gt;Vitis vinifera&lt;/i&gt; L. extracts, hesperidin and chromium in combination with an isocaloric diet on glucose and lipid metabolism in subjects with impaired fasting blood glucose: a single-center, controlled, randomized, parallel-arm, double-blind clinical trial."],"pmcid":["PMC12558782"],"pubmed_authors":["Borromeo L","Santonastaso S","Piccinocchi R","El-Seedi H","Greco A","Xiao X","Sacchi R","De Lellis LF","Baldi A","Buccato DG","Cerqua A","Daglia M","Morone MV","Ullah H","Larsen DS","Riccioni CV","Piccinocchi G","Di Minno A"],"additional_accession":[]},"is_claimable":false,"name":"Impact of a food supplement containing &lt;i&gt;Citrus limon&lt;/i&gt; L. Osbeck and &lt;i&gt;Vitis vinifera&lt;/i&gt; L. extracts, hesperidin and chromium in combination with an isocaloric diet on glucose and lipid metabolism in subjects with impaired fasting blood glucose: a single-center, controlled, randomized, parallel-arm, double-blind clinical trial.","description":"<h4>Introduction</h4>Impaired fasting glycemia (IFG) puts carriers at a significantly higher risk of developing type 2 diabetes and cardiovascular disease. Lifestyle changes, such as increased physical activity and a healthy diet rich in fiber and low in sugar, can often reverse prediabetes and significantly reduce the risk of progressing to type 2 diabetes metabolic disorders, especially diabetes (1).<h4>Methods</h4>This randomized clinical trial aims to evaluate the efficacy and tolerability of a food supplement (FS) containing <i>Citrus limon</i> L. Osbeck and <i>Vitis vinifera</i> L. extracts, hesperidin from <i>Citrus sinensis</i> L. Osbeck, and chromium, in individuals with impaired fasting blood glucose , with the final goal of investigating whether the use of a combination of ingre","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025","modification":"2026-05-15T03:17:47.341Z","creation":"2026-05-15T03:11:58.328Z"},"accession":"S-EPMC12558782","cross_references":{"pubmed":["41164360"],"doi":["10.3389/fnut.2025.1671102"]}}