biostudies-literatureUnknown53(10)Ge YObjectiveArthritis is an acute or chronic inflammatory joint disease characterized by pain and stiffness that typically worsen with aging. It is often accompanied with joint rigidity, cartilage degeneration, and pathological changes, such as monocyte infiltration, inflammation, synovial swelling, and mass formation. Osteoarthritis and rheumatoid arthritis are the two most common forms of arthritis worldwide. The atherogenic index of plasma, which reflects lipid metabolism, may influence arthritis progression. This study aimed to investigate the relationship between the atherogenic index of plasma and arthritis among adults in the United States.MethodsUsing the National Health and Nutrition Examination Survey data (2005-2018), 12,273 individuals (representing 74.2 million people) with complThe Journal of international medical research3000605251383294https://www.ebi.ac.uk/biostudies/studies/S-EPMC12559633biostudies-literatureRelationship between the atherogenic index of plasma and arthritis in American adults: Findings from the National Health and Nutrition Examination Survey 2005-2018.PMC12559633He TYang LZhang JGe YXie JLuo YZhang LOu XWang YSun ZfalseRelationship between the atherogenic index of plasma and arthritis in American adults: Findings from the National Health and Nutrition Examination Survey 2005-2018.ObjectiveArthritis is an acute or chronic inflammatory joint disease characterized by pain and stiffness that typically worsen with aging. It is often accompanied with joint rigidity, cartilage degeneration, and pathological changes, such as monocyte infiltration, inflammation, synovial swelling, and mass formation. Osteoarthritis and rheumatoid arthritis are the two most common forms of arthritis worldwide. The atherogenic index of plasma, which reflects lipid metabolism, may influence arthritis progression. This study aimed to investigate the relationship between the atherogenic index of plasma and arthritis among adults in the United States.MethodsUsing the National Health and Nutrition Examination Survey data (2005-2018), 12,273 individuals (representing 74.2 million people) with compl2025-01-01T00:00:00Z2025 Oct2026-06-05T06:54:14.897Z2026-05-13T14:29:07.105ZS-EPMC125596334113092410.1177/03000605251383294