{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["14(10)"],"submitter":["De Luca M"],"pubmed_abstract":["<b>Background/Objectives</b>: <i>Streptococcus pyogenes</i> (Group A Streptococcus, GAS) is a major human pathogen that causes a wide spectrum of diseases. While mild infections like pharyngitis and impetigo are common, severe and invasive infections, though less frequent, pose significant health risks, particularly in children. In recent years, the re-emergence of hypervirulent GAS strains has heightened global concern. Nowadays, the absence of universally accepted guidelines compels clinicians to rely on a combination of clinical judgment, microbiological data and available evidence to manage these infections effectively. Our aim was to assess the current management of invasive GAS (iGAS) infections in Italy and the variability in therapeutic and preventive approaches. <b>Methods</b>: A "],"journal":["Antibiotics (Basel, Switzerland)"],"pagination":["970"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC12561913"],"repository":["biostudies-literature"],"pubmed_title":["Current Clinical Practice on the Management of Invasive Streptococcus Pyogenes Infections in Children: A Survey-Based Study."],"pmcid":["PMC12561913"],"pubmed_authors":["Zama D","Chiappini E","Colomba C","Romani L","Nicolini G","De Luca M","Bosis S","Lo Vecchio A","D'Amore C","Tripiciano C","Ciofi Degli Atti ML","Pagano F","Garazzino S"],"additional_accession":[]},"is_claimable":false,"name":"Current Clinical Practice on the Management of Invasive Streptococcus Pyogenes Infections in Children: A Survey-Based Study.","description":"<b>Background/Objectives</b>: <i>Streptococcus pyogenes</i> (Group A Streptococcus, GAS) is a major human pathogen that causes a wide spectrum of diseases. While mild infections like pharyngitis and impetigo are common, severe and invasive infections, though less frequent, pose significant health risks, particularly in children. In recent years, the re-emergence of hypervirulent GAS strains has heightened global concern. Nowadays, the absence of universally accepted guidelines compels clinicians to rely on a combination of clinical judgment, microbiological data and available evidence to manage these infections effectively. Our aim was to assess the current management of invasive GAS (iGAS) infections in Italy and the variability in therapeutic and preventive approaches. <b>Methods</b>: A ","dates":{"release":"2025-01-01T00:00:00Z","publication":"2025 Sep","modification":"2026-05-14T03:19:53.833Z","creation":"2026-05-14T03:12:30.764Z"},"accession":"S-EPMC12561913","cross_references":{"pubmed":["41148663"],"doi":["10.3390/antibiotics14100970"]}}